Celecoxib cocrystal polymorphs with cyclic amides: Synthons of a sulfonamide drug with carboxamide coformers

Geetha Bolla, Sudhir Mittapalli, Ashwini Nangia

Research output: Contribution to journalArticlepeer-review

58 Scopus citations

Abstract

The trimorphic cocrystals of celecoxib with δ-valerolactam contain sulfonamide dimers and catemers together with carboxamide dimers, whereas the caprolactam cocrystal is sustained by a SO2N-H⋯H-NOC heterosynthon. The alternation of synthons with even-odd ring coformers offers a crystal engineering approach to sulfonamide-carboxamide cocrystals.

Original languageEnglish
Pages (from-to)24-27
Number of pages4
JournalCrystEngComm
Volume16
Issue number1
DOIs
StatePublished - 7 Jan 2014
Externally publishedYes

ASJC Scopus subject areas

  • General Chemistry
  • General Materials Science
  • Condensed Matter Physics

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