Cell activation and signal initiation

Research output: Contribution to journalArticlepeer-review


Studying the mechanisms by which growth factors activate cellular functions has provided important insights into the normal pathways of cell growth and differentiation. Furthermore, such a study affords a basis for understanding how subversion of these pathways by defective proto-oncogenes leads to cancer. The interaction between growth factors and their appropriate receptors initiates a cascade of biochemical events during which protein phosphorylation and dephosphorylation play key roles in regulation of signal transduction and activation of effector functions. A UCLA Symposium on Cell Activation and Signal Initiation* * Organized by E. Dennis, T. Hunter and M. Berridge and held on 17-24 April 1988 in Keystone, Colorado. Abstracts have been published in the Journal of Cellular Biochemistry. highlighted recent progress in this area.

Original languageEnglish
Pages (from-to)253-255
Number of pages3
JournalTrends in Immunology
Issue number1-12
StatePublished - 1 Dec 1988

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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