Studying the mechanisms by which growth factors activate cellular functions has provided important insights into the normal pathways of cell growth and differentiation. Furthermore, such a study affords a basis for understanding how subversion of these pathways by defective proto-oncogenes leads to cancer. The interaction between growth factors and their appropriate receptors initiates a cascade of biochemical events during which protein phosphorylation and dephosphorylation play key roles in regulation of signal transduction and activation of effector functions. A UCLA Symposium on Cell Activation and Signal Initiation* * Organized by E. Dennis, T. Hunter and M. Berridge and held on 17-24 April 1988 in Keystone, Colorado. Abstracts have been published in the Journal of Cellular Biochemistry. highlighted recent progress in this area.
|Number of pages||3|
|Journal||Trends in Immunology|
|State||Published - 1 Dec 1988|
ASJC Scopus subject areas
- Immunology and Allergy