Cell activation and signal initiation

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Studying the mechanisms by which growth factors activate cellular functions has provided important insights into the normal pathways of cell growth and differentiation. Furthermore, such a study affords a basis for understanding how subversion of these pathways by defective proto-oncogenes leads to cancer. The interaction between growth factors and their appropriate receptors initiates a cascade of biochemical events during which protein phosphorylation and dephosphorylation play key roles in regulation of signal transduction and activation of effector functions. A UCLA Symposium on Cell Activation and Signal Initiation highlighted recent progress in this area.

Original languageEnglish
Pages (from-to)251-252
Number of pages2
JournalImmunology Today
Issue number9
StatePublished - 1 Jan 1988

ASJC Scopus subject areas

  • Immunology


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