Cellular immunity in patients with multiple primary tumors

Arie Bartal; Robert Haasz; Mariana Steiner; Yoram Cohen; Eliezer Robinson

doi:10.1007/BF00205437

Cellular immunity in patients with multiple primary tumors

Arie Bartal, Robert Haasz, Mariana Steiner, Yoram Cohen, Eliezer Robinson

Research output: Contribution to journal › Article › peer-review

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Abstract

Immunological studies for evaluation of cellular immunity were carried out on 22 patients who had two primary malignant tumors and who had no evidence of active disease. The tests performed were for skin reactivity to 3 recall antigens, PPD, Candidine, and Streptokinase and in vitro lymphocyte stimulation by PHA. Of these, 6 patients were anergic to all three recall antigens and 5 other patients to two out of three antigens. A depression of the in vitro reactivity was encountered in 11 patients. The immune incompetence was more evident in patients with simultaneous tumors than in those with metachroneous tumors. The longer the interval between the appearance of the primary and the secondary tumors, the less immunosuppression was seen.

Original language	English
Pages (from-to)	195-199
Number of pages	5
Journal	Cancer Immunology, Immunotherapy
Volume	2
Issue number	3
DOIs	https://doi.org/10.1007/BF00205437
State	Published - 1 Jan 1977
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Oncology
Cancer Research

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10.1007/BF00205437

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title = "Cellular immunity in patients with multiple primary tumors",

abstract = "Immunological studies for evaluation of cellular immunity were carried out on 22 patients who had two primary malignant tumors and who had no evidence of active disease. The tests performed were for skin reactivity to 3 recall antigens, PPD, Candidine, and Streptokinase and in vitro lymphocyte stimulation by PHA. Of these, 6 patients were anergic to all three recall antigens and 5 other patients to two out of three antigens. A depression of the in vitro reactivity was encountered in 11 patients. The immune incompetence was more evident in patients with simultaneous tumors than in those with metachroneous tumors. The longer the interval between the appearance of the primary and the secondary tumors, the less immunosuppression was seen.",

author = "Arie Bartal and Robert Haasz and Mariana Steiner and Yoram Cohen and Eliezer Robinson",

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AU - Bartal, Arie

AU - Haasz, Robert

AU - Steiner, Mariana

AU - Cohen, Yoram

AU - Robinson, Eliezer

PY - 1977/1/1

Y1 - 1977/1/1

N2 - Immunological studies for evaluation of cellular immunity were carried out on 22 patients who had two primary malignant tumors and who had no evidence of active disease. The tests performed were for skin reactivity to 3 recall antigens, PPD, Candidine, and Streptokinase and in vitro lymphocyte stimulation by PHA. Of these, 6 patients were anergic to all three recall antigens and 5 other patients to two out of three antigens. A depression of the in vitro reactivity was encountered in 11 patients. The immune incompetence was more evident in patients with simultaneous tumors than in those with metachroneous tumors. The longer the interval between the appearance of the primary and the secondary tumors, the less immunosuppression was seen.

AB - Immunological studies for evaluation of cellular immunity were carried out on 22 patients who had two primary malignant tumors and who had no evidence of active disease. The tests performed were for skin reactivity to 3 recall antigens, PPD, Candidine, and Streptokinase and in vitro lymphocyte stimulation by PHA. Of these, 6 patients were anergic to all three recall antigens and 5 other patients to two out of three antigens. A depression of the in vitro reactivity was encountered in 11 patients. The immune incompetence was more evident in patients with simultaneous tumors than in those with metachroneous tumors. The longer the interval between the appearance of the primary and the secondary tumors, the less immunosuppression was seen.

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JO - Cancer Immunology, Immunotherapy

JF - Cancer Immunology, Immunotherapy

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ER -

Cellular immunity in patients with multiple primary tumors

Abstract

ASJC Scopus subject areas

UN SDGs

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