TY - JOUR
T1 - Central (intraosseous) myofibroma of the mandible
T2 - clinical, radiologic, and histopathologic features of a rare lesion
AU - Allon, Irit
AU - Vered, Marilena
AU - Buchner, Amos
AU - Dayan, Dan
N1 - Funding Information:
The study was supported by the Ed and Herb Stein Chair in Oral Pathology, Tel Aviv University.
PY - 2007/4/1
Y1 - 2007/4/1
N2 - Objective: Myofibroma frequently manifests as a solitary soft tissue tumor and less as simultaneous multiple tumors in both soft tissues and bones. The present study evaluated clinical, radiological, and histopathologic features of myofibroma of the jaws. Study design: Nineteen cases from the literature and 4 new cases were analyzed. Results: At initial diagnosis, age ranged from birth to 34 years (mean 7.2 years, median 6 years). Male/female ratio was 2.3:1. Myofibromas were radiolucent solitary lesions located solely in the mandible: 70% unilocular, 30% multilocular; 67% with well-defined borders. Conservative treatment was performed on 75% of the patients; 25% underwent partial jaw resection. Where information was provided, no lesion recurred during 6-month to 17-year follow-up. Conclusion: Although rare, myofibroma of the mandible should be considered in the differential diagnosis of radiolucent lesions (particularly unilocular), especially in children. Treatment of choice is conservative surgery to minimize potential functional and/or esthetic damage.
AB - Objective: Myofibroma frequently manifests as a solitary soft tissue tumor and less as simultaneous multiple tumors in both soft tissues and bones. The present study evaluated clinical, radiological, and histopathologic features of myofibroma of the jaws. Study design: Nineteen cases from the literature and 4 new cases were analyzed. Results: At initial diagnosis, age ranged from birth to 34 years (mean 7.2 years, median 6 years). Male/female ratio was 2.3:1. Myofibromas were radiolucent solitary lesions located solely in the mandible: 70% unilocular, 30% multilocular; 67% with well-defined borders. Conservative treatment was performed on 75% of the patients; 25% underwent partial jaw resection. Where information was provided, no lesion recurred during 6-month to 17-year follow-up. Conclusion: Although rare, myofibroma of the mandible should be considered in the differential diagnosis of radiolucent lesions (particularly unilocular), especially in children. Treatment of choice is conservative surgery to minimize potential functional and/or esthetic damage.
UR - http://www.scopus.com/inward/record.url?scp=33947526468&partnerID=8YFLogxK
U2 - 10.1016/j.tripleo.2006.08.026
DO - 10.1016/j.tripleo.2006.08.026
M3 - Article
C2 - 17150381
AN - SCOPUS:33947526468
SN - 1079-2104
VL - 103
SP - e45-e53
JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
JF - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
IS - 4
ER -