Central nervous system complications secondary to oto-rhinologic infections. An analysis of 39 pediatric cases

Mordechai Kraus, Ferit Tovi

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Fifty-eight central nervous system complications were noted in 39 pediatric patients with a primary oto-rhinological infection. The ages ranged from 1 to 15 years. Eleven patients (25%) had more than one complication. 12.8% of the cases died. Leptomeningitis was the most common intracranial complication (54%) Lateral sinus thrombosis (LST) occurring in 10 patients (26%) was accompanied with other intracranial abnormalities in 80% of cases. Brain abscess as an initial or concomitant complication was associated with the highest mortality rates (40%). In two of these fatal cases multiple brain abscesses were detected. The low incidence of intracranial infections secondary to oto-rhinologic infections and the masking effect of antibiotics present difficulties in the early recognition of the CNS complication. Despite the value of the modern imaging techniques in the investigation of the CNS complication, the clinical oto-rhinologic examination is of paramount importance in detecting the original infection in the pneumatic spaces of the upper respiratory tract. Additionally, bone scans were found of value in demonstrating the osteitic process of these cases.

Original languageEnglish
Pages (from-to)217-226
Number of pages10
JournalInternational Journal of Pediatric Otorhinolaryngology
Volume24
Issue number3
DOIs
StatePublished - 1 Jan 1992
Externally publishedYes

Keywords

  • Brain abscess
  • Extradural abscess
  • Lateral sinus thrombosis
  • Meningitis
  • Subdural empyema

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Otorhinolaryngology

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