Changes in lipid composition and osmotic fragility of erythrocytes of hamster induced by heat exposure

Pieter J.C. Kuiper, Avinoam Livne, Naomi Meyerstein

Research output: Contribution to journalArticlepeer-review

46 Scopus citations

Abstract

In attempting to explain the increased osmotic fragility of hamster erythrocytes following a prolonged exposure of the animals to an elevated ambient temperature, the lipids and fatty acids of the red blood cells were studied. The heat exposure of the hamsters resulted in a lower cholesterol/phospholipids ratio, a lower content of phosphatidyl choline and sphingomyelin and a higher content of phosphatidyl ethanolamine and phosphatidyl serine. In erythrocytes of control hamsters, the major fatty acid of phosphatidyl choline, phosphatidyl serine and sphingomyelin is linolenic acid, while it is palmitic acid in the erythrocytes of the heat-exposed animals. Each of these modifications in the lipid profile of the red blood cells may contribute to the difference in osmotic fragility between the two groups of hamsters.

Original languageEnglish
Pages (from-to)300-305
Number of pages6
JournalBiochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
Volume248
Issue number2
DOIs
StatePublished - 5 Nov 1971
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Endocrinology

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