Diseases resulting from impaired ion channel function-channelopathies-are increasingly recognized pathologies in human cardiovascular medicine.1 Understanding the molecular basis of an ion channel disease has provided new opportunities for screening, early diagnosis, and therapy of these commonly life-threatening conditions. 2, 3 A case in point is the identification of molecular genetic defects in inwardly rectifying potassium (Kir, KCNJ) channels.
|Title of host publication||Electrical Diseases of the Heart|
|Subtitle of host publication||Genetics, Mechanisms, Treatment, Prevention|
|Number of pages||11|
|State||Published - 1 Dec 2008|