In both natural language and biology, signs are polysemous, with a range of possible meanings before interaction-in-context determines their value. What is the meaning of polysemy? What is the role of polysemy in linguistic and biological systems? In this chapter, I present the idea that organisms function by using two different, orthogonal modes of communication: digital (involving discrete units) and analogue (involving continuous values). I argue that the polysemy of the sign, here metaphorically interpreted as a superposition, is necessary for orchestrating these modes and tying them to a concrete context of interaction.