Characterization of embryonic liver suppressor cells by peanut agglutinin

Hanna Rabinovich, Tehila Umiel, Yair Reisner, Nathan Sharon, Amiela Globerson

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Liver cells of 19-day-old mouse embryos were separated by peanut agglutinin (PNA) into two fractions. The fraction agglutinated with the PNA was found to be enriched for cells capable of suppressing the MLC reaction and the response to the mitogens Con A, PHA, and LPS. The fraction not agglutinated by PNA was significantly less suppressive. The response to DxS was not suppressed by any of these fractions. On the other hand, the response to LPS and DxS, but not to Con A or PHA, was expressed by the nonagglutinated fraction. It is thus inferred that the suppressor cells in the embryonic liver are separable from the potentially reactive cells.

Original languageEnglish
Pages (from-to)347-355
Number of pages9
JournalCellular Immunology
Volume47
Issue number2
DOIs
StatePublished - 1 Jan 1979
Externally publishedYes

Fingerprint

Dive into the research topics of 'Characterization of embryonic liver suppressor cells by peanut agglutinin'. Together they form a unique fingerprint.

Cite this