Chemical waves and internal energy during cooperative self-wiring of neural nets

Ronen Segev, Eshel Ben Jacob

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


During embryonic morpho-genesis, a collection of individual neurons turns into a functioning network with unique capabilities. We proposed a navigational strategy for neurite growth cones, based on chemical signaling. The model incorporates stationary units representing the cells, and walkers representing the growth cones. The walkers migrate in response to chemotactic substances emitted by the cells. The chemotactic responses of the walker is determined by the dynamics of the walker's internal energy. We further propose that the embryonic environment acts as an excitable media in which chemical waves are formed and provide a mechanism for regulation and navigation over long distances.

Original languageEnglish
Pages (from-to)875-879
Number of pages5
StatePublished - 1 Jun 2001
Externally publishedYes


  • Chemical waves
  • Internal energy
  • Neural networks
  • Self-wiring

ASJC Scopus subject areas

  • Computer Science Applications
  • Cognitive Neuroscience
  • Artificial Intelligence


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