Chemically-modified starches for targeted drug delivery

J. Kost, S. Shefer

Research output: Contribution to journalConference articlepeer-review


The objective of this research focused on the evaluation of chemically-modified starches as a possible natural polymeric matrix for enzymatically controlled targeted drug delivery. The objectives of this work were to evaluate chemically modified corn starch as drug delivery matrices for: 1) Oral targeted delivery of drugs to the intestine and 2) direct intra-arterial injection in attempt to temporary alter blood flow and thus to target drugs into the temporal blockage regions. Intra-arterial injection of biodegradable starch particles can be used to produce a temporal tumor chemoembolism in cancer chemotherapy thereby increasing absorption time and tissue uptake of the drug by the tumor organs.

Original languageEnglish
Pages (from-to)47-50
Number of pages4
JournalPolymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering
StatePublished - 1 Dec 1990
EventProceedings of the ACS Division of Polymeric Materials: Science and Engineering - Washington, DC, USA
Duration: 26 Aug 199031 Aug 1990

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Polymers and Plastics


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