Abstract
The objective of this research focused on the evaluation of chemically-modified starches as a possible natural polymeric matrix for enzymatically controlled targeted drug delivery. The objectives of this work were to evaluate chemically modified corn starch as drug delivery matrices for: 1) Oral targeted delivery of drugs to the intestine and 2) direct intra-arterial injection in attempt to temporary alter blood flow and thus to target drugs into the temporal blockage regions. Intra-arterial injection of biodegradable starch particles can be used to produce a temporal tumor chemoembolism in cancer chemotherapy thereby increasing absorption time and tissue uptake of the drug by the tumor organs.
| Original language | English |
|---|---|
| Pages (from-to) | 47-50 |
| Number of pages | 4 |
| Journal | Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering |
| Volume | 63 |
| State | Published - 1 Dec 1990 |
| Event | Proceedings of the ACS Division of Polymeric Materials: Science and Engineering - Washington, DC, USA Duration: 26 Aug 1990 → 31 Aug 1990 |
ASJC Scopus subject areas
- Chemical Engineering (miscellaneous)
- Polymers and Plastics
