Chemiluminescent optical fiber immunosensor for the detection of anti-West Nile virus IgG

Sebastien Herrmann, Boaz Leshem, Shimi Landes, Bracha Rager-Zisman, Robert S. Marks

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

An ELISA-based optical fiber methodology developed for the detection of anti-West Nile virus IgG antibodies in serum was compared to standard colorimetric and chemiluminescent ELISA based on microtiter plates. Colorimetric ELISA was the least sensitive, especially at high titer dilutions. The fiber-optic immunosensor based on the same ELISA immunological rationale was the most sensitive technique.

Original languageEnglish
Pages (from-to)6-14
Number of pages9
JournalTalanta
Volume66
Issue number1
DOIs
StatePublished - 31 Mar 2005

Keywords

  • Chemiluminescence
  • ELISA
  • Optical fiber immunosensor
  • West Nile virus

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