Cholinergic excitation induces activity-dependent electrophysiological and transcriptional responses in hippocampal slices

Alon Friedman, Daniela Kaufer, Lev Pavlovsky, Hermona Soreq

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

To explore the correlations between short-term neurophysiological events initiated by over-activation of acetylcholine receptors, and long-lasting changes in brain function, we combined electrophysiology and PCR-based measurements in hippocampal slices or live mice subjected to stress or drug- induced cholinergic activation. Our findings reveal a common cascade of neuronal events resulting in delayed suppression of cholinergic transmission.

Original languageEnglish
Pages (from-to)329-335
Number of pages7
JournalJournal of Physiology Paris
Volume92
Issue number3-4
DOIs
StatePublished - 1 Jan 1998

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