Chromatic polymer assays for the analysis of lipid and lipoprotein peroxidation

Raz Jelinek; Sofiya Kolusheva; Ella Mann; Michael Aviram

doi:10.1002/lite.201500010

Chromatic polymer assays for the analysis of lipid and lipoprotein peroxidation

Raz Jelinek, Sofiya Kolusheva, Ella Mann, Michael Aviram

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Evaluation of the extent of lipoprotein oxidation and the effects of therapeutic and dietary agents upon lipid peroxidation processes are critical in understanding and combating atherosclerotic diseases. Bioanalytical chromatic assays based upon polydiacetylene (PDA) have recently emerged as a useful platform for analysis of lipoprotein oxidation. This article describes the principles of PDA-based sensing, and its application to the study of lipids peroxidation, both in purified lipoprotein samples, as well as in blood plasma specimens.

Original language	English
Pages (from-to)	86-89
Number of pages	4
Journal	Lipid Technology
Volume	27
Issue number	4
DOIs	https://doi.org/10.1002/lite.201500010
State	Published - 1 Apr 2015

ASJC Scopus subject areas

Control and Systems Engineering
Food Science
General Biochemistry, Genetics and Molecular Biology

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10.1002/lite.201500010

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abstract = "Evaluation of the extent of lipoprotein oxidation and the effects of therapeutic and dietary agents upon lipid peroxidation processes are critical in understanding and combating atherosclerotic diseases. Bioanalytical chromatic assays based upon polydiacetylene (PDA) have recently emerged as a useful platform for analysis of lipoprotein oxidation. This article describes the principles of PDA-based sensing, and its application to the study of lipids peroxidation, both in purified lipoprotein samples, as well as in blood plasma specimens.",

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AU - Kolusheva, Sofiya

AU - Mann, Ella

AU - Aviram, Michael

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Y1 - 2015/4/1

N2 - Evaluation of the extent of lipoprotein oxidation and the effects of therapeutic and dietary agents upon lipid peroxidation processes are critical in understanding and combating atherosclerotic diseases. Bioanalytical chromatic assays based upon polydiacetylene (PDA) have recently emerged as a useful platform for analysis of lipoprotein oxidation. This article describes the principles of PDA-based sensing, and its application to the study of lipids peroxidation, both in purified lipoprotein samples, as well as in blood plasma specimens.

AB - Evaluation of the extent of lipoprotein oxidation and the effects of therapeutic and dietary agents upon lipid peroxidation processes are critical in understanding and combating atherosclerotic diseases. Bioanalytical chromatic assays based upon polydiacetylene (PDA) have recently emerged as a useful platform for analysis of lipoprotein oxidation. This article describes the principles of PDA-based sensing, and its application to the study of lipids peroxidation, both in purified lipoprotein samples, as well as in blood plasma specimens.

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Chromatic polymer assays for the analysis of lipid and lipoprotein peroxidation

Abstract

ASJC Scopus subject areas

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