Chromatic polymer assays for the analysis of lipid and lipoprotein peroxidation

Raz Jelinek, Sofiya Kolusheva, Ella Mann, Michael Aviram

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Evaluation of the extent of lipoprotein oxidation and the effects of therapeutic and dietary agents upon lipid peroxidation processes are critical in understanding and combating atherosclerotic diseases. Bioanalytical chromatic assays based upon polydiacetylene (PDA) have recently emerged as a useful platform for analysis of lipoprotein oxidation. This article describes the principles of PDA-based sensing, and its application to the study of lipids peroxidation, both in purified lipoprotein samples, as well as in blood plasma specimens.

Original languageEnglish
Pages (from-to)86-89
Number of pages4
JournalLipid Technology
Volume27
Issue number4
DOIs
StatePublished - 1 Apr 2015
Externally publishedYes

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