Chronic eosinophilic leukemia complicated by epidural myeloblastoma

Alexander Dvilansky; Michael L. Alkan; Winston Ho; Helena Kaplan; Paskal Tiberin; Bracha Rachmilewitz

doi:10.1159/000208205

Chronic eosinophilic leukemia complicated by epidural myeloblastoma

Alexander Dvilansky
, Michael L. Alkan
, Winston Ho
, Helena Kaplan
, Paskal Tiberin
, Bracha Rachmilewitz

Medical School for International Health

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Epidural myeloblastoma, which compressed the spinal cord, was the first evidence for chronic granulocytic leukemia, eosinophilic type, Ph chromosome negative. This manifestation was preceded by 3 years follow-up of a patient with persistent eosinophilia of 60% mature eosinophils. The only clues for the diagnosis of leukemia were splenomegaly and high serum vitamin B₁₂, most of which was bound to transcobalamin I. The latter finding presents a useful diagnostic criterium in myeloproliferative disorders.

Original language	English
Pages (from-to)	356-361
Number of pages	6
Journal	Acta Haematologica
Volume	53
Issue number	6
DOIs	https://doi.org/10.1159/000208205
State	Published - 1 Jan 1975

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Eosinophilic leukemia
Myeloblastoma
Transcobalamins
Vitamin B<inf>12</inf>

ASJC Scopus subject areas

Hematology

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10.1159/000208205

Cite this

@article{5d4a7741072d41498b2d6f4ec96704ed,

title = "Chronic eosinophilic leukemia complicated by epidural myeloblastoma",

abstract = "Epidural myeloblastoma, which compressed the spinal cord, was the first evidence for chronic granulocytic leukemia, eosinophilic type, Ph chromosome negative. This manifestation was preceded by 3 years follow-up of a patient with persistent eosinophilia of 60\% mature eosinophils. The only clues for the diagnosis of leukemia were splenomegaly and high serum vitamin B12, most of which was bound to transcobalamin I. The latter finding presents a useful diagnostic criterium in myeloproliferative disorders.",

keywords = "Eosinophilic leukemia, Myeloblastoma, Transcobalamins, Vitamin B<inf>12</inf>",

author = "Alexander Dvilansky and Alkan, \{Michael L.\} and Winston Ho and Helena Kaplan and Paskal Tiberin and Bracha Rachmilewitz",

year = "1975",

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day = "1",

doi = "10.1159/000208205",

language = "English",

volume = "53",

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journal = "Acta Haematologica",

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TY - JOUR

T1 - Chronic eosinophilic leukemia complicated by epidural myeloblastoma

AU - Dvilansky, Alexander

AU - Alkan, Michael L.

AU - Ho, Winston

AU - Kaplan, Helena

AU - Tiberin, Paskal

AU - Rachmilewitz, Bracha

PY - 1975/1/1

Y1 - 1975/1/1

N2 - Epidural myeloblastoma, which compressed the spinal cord, was the first evidence for chronic granulocytic leukemia, eosinophilic type, Ph chromosome negative. This manifestation was preceded by 3 years follow-up of a patient with persistent eosinophilia of 60% mature eosinophils. The only clues for the diagnosis of leukemia were splenomegaly and high serum vitamin B12, most of which was bound to transcobalamin I. The latter finding presents a useful diagnostic criterium in myeloproliferative disorders.

AB - Epidural myeloblastoma, which compressed the spinal cord, was the first evidence for chronic granulocytic leukemia, eosinophilic type, Ph chromosome negative. This manifestation was preceded by 3 years follow-up of a patient with persistent eosinophilia of 60% mature eosinophils. The only clues for the diagnosis of leukemia were splenomegaly and high serum vitamin B12, most of which was bound to transcobalamin I. The latter finding presents a useful diagnostic criterium in myeloproliferative disorders.

KW - Eosinophilic leukemia

KW - Myeloblastoma

KW - Transcobalamins

KW - Vitamin B<inf>12</inf>

UR - https://www.scopus.com/pages/publications/0016734723

U2 - 10.1159/000208205

DO - 10.1159/000208205

M3 - Article

C2 - 808941

AN - SCOPUS:0016734723

SN - 0001-5792

VL - 53

SP - 356

EP - 361

JO - Acta Haematologica

JF - Acta Haematologica

IS - 6

ER -

Chronic eosinophilic leukemia complicated by epidural myeloblastoma

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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