TY - JOUR
T1 - Chronic hypertension is an independent risk factor for preeclampsia and preterm delivery in women with rheumatologic diseases
T2 - A population-based study
AU - Mayer, Amit
AU - Erez, Offer
AU - Novack, Lena
AU - Bashiri, Asher
AU - Wiznitzer, Arnon
AU - Mazor, Moshe
PY - 2007/1/1
Y1 - 2007/1/1
N2 - Objective: The objective was to determine the prevalence of maternal and perinatal complications among patients with rheumatologic diseases (RD) and to investigate the maternal risk factors for preeclampsia and preterm delivery among RD patients. Study design: A retrospective population-based cohort study was conducted. The study group comprised women with RD; the control group comprised patients without RD. The obstetric and neonatal outcomes of the groups were compared, and the data were obtained from a computerized database. Results: During the study period, there were 179 deliveries by 125 women with RD. The prevalence of severe preeclampsia, chronic hypertension, pregestational diabetes, oligohydramnios, preterm deliveries and cesarean sections was significantly higher in the RD group than in the control group. Mean birth weight was significantly lower in the study group compared with the general population. Maternal RD was found to be an independent risk factor for preterm delivery and severe preeclampsia (OR 3.59; 95% CI: 2.52-5.11; OR 3.05; 95% CI: 1.44-6.45, respectively). The presence of chronic hypertension in patients with RD was found to be an independent risk factor for severe preeclampsia and preterm delivery (OR 12.2; 95% CI: 2.1-69.8; OR 3.8; 95% CI: 1.1-12.7, respectively). Conclusion: Chronic hypertension is an independent risk factor for preterm delivery and severe preeclampsia among RD patients.
AB - Objective: The objective was to determine the prevalence of maternal and perinatal complications among patients with rheumatologic diseases (RD) and to investigate the maternal risk factors for preeclampsia and preterm delivery among RD patients. Study design: A retrospective population-based cohort study was conducted. The study group comprised women with RD; the control group comprised patients without RD. The obstetric and neonatal outcomes of the groups were compared, and the data were obtained from a computerized database. Results: During the study period, there were 179 deliveries by 125 women with RD. The prevalence of severe preeclampsia, chronic hypertension, pregestational diabetes, oligohydramnios, preterm deliveries and cesarean sections was significantly higher in the RD group than in the control group. Mean birth weight was significantly lower in the study group compared with the general population. Maternal RD was found to be an independent risk factor for preterm delivery and severe preeclampsia (OR 3.59; 95% CI: 2.52-5.11; OR 3.05; 95% CI: 1.44-6.45, respectively). The presence of chronic hypertension in patients with RD was found to be an independent risk factor for severe preeclampsia and preterm delivery (OR 12.2; 95% CI: 2.1-69.8; OR 3.8; 95% CI: 1.1-12.7, respectively). Conclusion: Chronic hypertension is an independent risk factor for preterm delivery and severe preeclampsia among RD patients.
KW - Chronic hypertension
KW - Preeclampsia
KW - Preterm delivery
KW - Rheumatologic disease
UR - http://www.scopus.com/inward/record.url?scp=34447581273&partnerID=8YFLogxK
U2 - 10.1016/j.ejogrb.2006.07.055
DO - 10.1016/j.ejogrb.2006.07.055
M3 - Article
C2 - 17010499
AN - SCOPUS:34447581273
SN - 0301-2115
VL - 133
SP - 157
EP - 163
JO - European Journal of Obstetrics and Gynecology and Reproductive Biology
JF - European Journal of Obstetrics and Gynecology and Reproductive Biology
IS - 2
ER -
