Citrinin Mycotoxin Contamination in Food and Feed: Impact on Agriculture, Human Health, and Detection and Management Strategies

Madhu Kamle; Dipendra Kumar Mahato; Akansha Gupta; Shikha Pandhi; Nitya Sharma; Bharti Sharma; Sadhna Mishra; Shalini Arora; Raman Selvakumar; Vivek Saurabh; Jyoti Dhakane-Lad; Manoj Kumar; Sreejani Barua; Arvind Kumar; Shirani Gamlath; Pradeep Kumar

doi:10.3390/toxins14020085

Citrinin Mycotoxin Contamination in Food and Feed: Impact on Agriculture, Human Health, and Detection and Management Strategies

Madhu Kamle, Dipendra Kumar Mahato, Akansha Gupta, Shikha Pandhi, Nitya Sharma, Bharti Sharma, Sadhna Mishra, Shalini Arora, Raman Selvakumar, Vivek Saurabh, Jyoti Dhakane-Lad, Manoj Kumar, Sreejani Barua, Arvind Kumar, Shirani Gamlath, Pradeep Kumar

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

Citrinin (CIT) is a mycotoxin produced by different species of Aspergillus, Penicillium, and Monascus. CIT can contaminate a wide range of foods and feeds at any time during the pre-harvest, harvest, and post-harvest stages. CIT can be usually found in beans, fruits, fruit and vegetable juices, herbs and spices, and dairy products, as well as red mold rice. CIT exerts nephrotoxic and genotoxic effects in both humans and animals, thereby raising concerns regarding the consumption of CIT-contaminated food and feed. Hence, to minimize the risk of CIT contamination in food and feed, understanding the incidence of CIT occurrence, its sources, and biosynthetic pathways could assist in the effective implementation of detection and mitigation measures. Therefore, this review aims to shed light on sources of CIT, its prevalence in food and feed, biosynthetic pathways, and genes involved, with a major focus on detection and management strategies to ensure the safety and security of food and feed.

Original language	English
Article number	85
Journal	Toxins
Volume	14
Issue number	2
DOIs	https://doi.org/10.3390/toxins14020085
State	Published - 1 Feb 2022
Externally published	Yes

Keywords

Citrinin
Detection and management strategies
Food and feed contamination
Human health

ASJC Scopus subject areas

Toxicology
Health, Toxicology and Mutagenesis

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10.3390/toxins14020085

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Kamle, M., Mahato, D. K., Gupta, A., Pandhi, S., Sharma, N., Sharma, B., Mishra, S., Arora, S., Selvakumar, R., Saurabh, V., Dhakane-Lad, J., Kumar, M., Barua, S., Kumar, A., Gamlath, S., & Kumar, P. (2022). Citrinin Mycotoxin Contamination in Food and Feed: Impact on Agriculture, Human Health, and Detection and Management Strategies. Toxins, 14(2), Article 85. https://doi.org/10.3390/toxins14020085

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title = "Citrinin Mycotoxin Contamination in Food and Feed: Impact on Agriculture, Human Health, and Detection and Management Strategies",

abstract = "Citrinin (CIT) is a mycotoxin produced by different species of Aspergillus, Penicillium, and Monascus. CIT can contaminate a wide range of foods and feeds at any time during the pre-harvest, harvest, and post-harvest stages. CIT can be usually found in beans, fruits, fruit and vegetable juices, herbs and spices, and dairy products, as well as red mold rice. CIT exerts nephrotoxic and genotoxic effects in both humans and animals, thereby raising concerns regarding the consumption of CIT-contaminated food and feed. Hence, to minimize the risk of CIT contamination in food and feed, understanding the incidence of CIT occurrence, its sources, and biosynthetic pathways could assist in the effective implementation of detection and mitigation measures. Therefore, this review aims to shed light on sources of CIT, its prevalence in food and feed, biosynthetic pathways, and genes involved, with a major focus on detection and management strategies to ensure the safety and security of food and feed.",

keywords = "Citrinin, Detection and management strategies, Food and feed contamination, Human health",

author = "Madhu Kamle and Mahato, {Dipendra Kumar} and Akansha Gupta and Shikha Pandhi and Nitya Sharma and Bharti Sharma and Sadhna Mishra and Shalini Arora and Raman Selvakumar and Vivek Saurabh and Jyoti Dhakane-Lad and Manoj Kumar and Sreejani Barua and Arvind Kumar and Shirani Gamlath and Pradeep Kumar",

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year = "2022",

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doi = "10.3390/toxins14020085",

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Kamle, M, Mahato, DK, Gupta, A, Pandhi, S, Sharma, N, Sharma, B, Mishra, S, Arora, S, Selvakumar, R, Saurabh, V, Dhakane-Lad, J, Kumar, M, Barua, S, Kumar, A, Gamlath, S & Kumar, P 2022, 'Citrinin Mycotoxin Contamination in Food and Feed: Impact on Agriculture, Human Health, and Detection and Management Strategies', Toxins, vol. 14, no. 2, 85. https://doi.org/10.3390/toxins14020085

TY - JOUR

T1 - Citrinin Mycotoxin Contamination in Food and Feed

T2 - Impact on Agriculture, Human Health, and Detection and Management Strategies

AU - Kamle, Madhu

AU - Mahato, Dipendra Kumar

AU - Gupta, Akansha

AU - Pandhi, Shikha

AU - Sharma, Nitya

AU - Sharma, Bharti

AU - Mishra, Sadhna

AU - Arora, Shalini

AU - Selvakumar, Raman

AU - Saurabh, Vivek

AU - Dhakane-Lad, Jyoti

AU - Kumar, Manoj

AU - Barua, Sreejani

AU - Kumar, Arvind

AU - Gamlath, Shirani

AU - Kumar, Pradeep

PY - 2022/2/1

Y1 - 2022/2/1

N2 - Citrinin (CIT) is a mycotoxin produced by different species of Aspergillus, Penicillium, and Monascus. CIT can contaminate a wide range of foods and feeds at any time during the pre-harvest, harvest, and post-harvest stages. CIT can be usually found in beans, fruits, fruit and vegetable juices, herbs and spices, and dairy products, as well as red mold rice. CIT exerts nephrotoxic and genotoxic effects in both humans and animals, thereby raising concerns regarding the consumption of CIT-contaminated food and feed. Hence, to minimize the risk of CIT contamination in food and feed, understanding the incidence of CIT occurrence, its sources, and biosynthetic pathways could assist in the effective implementation of detection and mitigation measures. Therefore, this review aims to shed light on sources of CIT, its prevalence in food and feed, biosynthetic pathways, and genes involved, with a major focus on detection and management strategies to ensure the safety and security of food and feed.

AB - Citrinin (CIT) is a mycotoxin produced by different species of Aspergillus, Penicillium, and Monascus. CIT can contaminate a wide range of foods and feeds at any time during the pre-harvest, harvest, and post-harvest stages. CIT can be usually found in beans, fruits, fruit and vegetable juices, herbs and spices, and dairy products, as well as red mold rice. CIT exerts nephrotoxic and genotoxic effects in both humans and animals, thereby raising concerns regarding the consumption of CIT-contaminated food and feed. Hence, to minimize the risk of CIT contamination in food and feed, understanding the incidence of CIT occurrence, its sources, and biosynthetic pathways could assist in the effective implementation of detection and mitigation measures. Therefore, this review aims to shed light on sources of CIT, its prevalence in food and feed, biosynthetic pathways, and genes involved, with a major focus on detection and management strategies to ensure the safety and security of food and feed.

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KW - Detection and management strategies

KW - Food and feed contamination

KW - Human health

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DO - 10.3390/toxins14020085

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AN - SCOPUS:85123753325

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VL - 14

JO - Toxins

JF - Toxins

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ER -

Citrinin Mycotoxin Contamination in Food and Feed: Impact on Agriculture, Human Health, and Detection and Management Strategies

Abstract

Keywords

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