TY - JOUR
T1 - Clinical and epidemiologic characteristics of non Hodgkin's lymphoma in Bedouins in the south of Israel
AU - Levi, Itai
AU - Feuchtwanger, Michal
AU - Rabinovich, Anat
AU - Grotto, Itamar
PY - 2013/1/1
Y1 - 2013/1/1
N2 - The presentation of Non Hodgkin's Lymphoma (NHL) may vary in relation to ethnicity or environmental effects. The objective of our study was to characterize NHL among the Negev Bedouin population, compared to the Jewish population. Retrospective data were collected for 45 Bedouin and 45 Jewish patients who were treated at Soroka University Medical Center between 1990 and 2007. Upon diagnosis, rates of aggressive NHL types, involvement of extra-lymphatic organs, as well as mean LDH were higher among Bedouin. Treatment response was poorer among the Bedouin: overall survival and disease-free survival were higher among Jews (mean of 145 and 168 months, respectively, compared with 70 and 45 months, respectively, among Bedouin; p < 0.01 for both). In summary, disease aggressiveness and poor response to treatment among the Negev Bedouin may shed some light on the pathogenicity of NHL and may indicate a need for more aggressive treatment in different ethnic groups.
AB - The presentation of Non Hodgkin's Lymphoma (NHL) may vary in relation to ethnicity or environmental effects. The objective of our study was to characterize NHL among the Negev Bedouin population, compared to the Jewish population. Retrospective data were collected for 45 Bedouin and 45 Jewish patients who were treated at Soroka University Medical Center between 1990 and 2007. Upon diagnosis, rates of aggressive NHL types, involvement of extra-lymphatic organs, as well as mean LDH were higher among Bedouin. Treatment response was poorer among the Bedouin: overall survival and disease-free survival were higher among Jews (mean of 145 and 168 months, respectively, compared with 70 and 45 months, respectively, among Bedouin; p < 0.01 for both). In summary, disease aggressiveness and poor response to treatment among the Negev Bedouin may shed some light on the pathogenicity of NHL and may indicate a need for more aggressive treatment in different ethnic groups.
KW - Bedouins
KW - Epidemiology
KW - Non Hodgkin's lymphoma
KW - Prognosis
UR - http://www.scopus.com/inward/record.url?scp=84891396205&partnerID=8YFLogxK
U2 - 10.1186/2193-1801-2-672
DO - 10.1186/2193-1801-2-672
M3 - Article
AN - SCOPUS:84891396205
SN - 2193-1801
VL - 2
SP - 1
EP - 7
JO - SpringerPlus
JF - SpringerPlus
IS - 1
M1 - 672
ER -