TY - JOUR
T1 - Clinical correlates of CSF cyclic nucleotides in schizophrenia
AU - Zohar, J.
AU - Biederman, J.
AU - Rimon, R.
AU - Ebstein, R.
AU - Belmaker, R. H.
PY - 1978/1/1
Y1 - 1978/1/1
N2 - The patient group consisted of 20 consecutive admissions of drug-free schizophrenic patients. Lumbar CSF was obtained and cyclic nucleotides, cAMP and cyclic guanosine monophosphate (cGMP), were measured. Diagnosis of simple schizophrenia, slow first remission, poor intermorbid adjustment, young age of onset, and absence of hallucinations are all significantly associated with increasing CSF cAMP. CSF cGMP was not significantly correlated with any clinical variable.
AB - The patient group consisted of 20 consecutive admissions of drug-free schizophrenic patients. Lumbar CSF was obtained and cyclic nucleotides, cAMP and cyclic guanosine monophosphate (cGMP), were measured. Diagnosis of simple schizophrenia, slow first remission, poor intermorbid adjustment, young age of onset, and absence of hallucinations are all significantly associated with increasing CSF cAMP. CSF cGMP was not significantly correlated with any clinical variable.
UR - http://www.scopus.com/inward/record.url?scp=0017891505&partnerID=8YFLogxK
U2 - 10.1176/ajp.135.2.253
DO - 10.1176/ajp.135.2.253
M3 - Article
AN - SCOPUS:0017891505
SN - 0002-953X
VL - 135
SP - 253
EP - 255
JO - American Journal of Psychiatry
JF - American Journal of Psychiatry
IS - 2
ER -