Clinical correlates of CSF cyclic nucleotides in schizophrenia

J. Zohar; J. Biederman; R. Rimon; R. Ebstein; R. H. Belmaker

doi:10.1176/ajp.135.2.253

Clinical correlates of CSF cyclic nucleotides in schizophrenia

J. Zohar
, J. Biederman
, R. Rimon
, R. Ebstein
, R. H. Belmaker

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The patient group consisted of 20 consecutive admissions of drug-free schizophrenic patients. Lumbar CSF was obtained and cyclic nucleotides, cAMP and cyclic guanosine monophosphate (cGMP), were measured. Diagnosis of simple schizophrenia, slow first remission, poor intermorbid adjustment, young age of onset, and absence of hallucinations are all significantly associated with increasing CSF cAMP. CSF cGMP was not significantly correlated with any clinical variable.

Original language	English
Pages (from-to)	253-255
Number of pages	3
Journal	American Journal of Psychiatry
Volume	135
Issue number	2
DOIs	https://doi.org/10.1176/ajp.135.2.253
State	Published - 1 Jan 1978

ASJC Scopus subject areas

Psychiatry and Mental health

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10.1176/ajp.135.2.253

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title = "Clinical correlates of CSF cyclic nucleotides in schizophrenia",

abstract = "The patient group consisted of 20 consecutive admissions of drug-free schizophrenic patients. Lumbar CSF was obtained and cyclic nucleotides, cAMP and cyclic guanosine monophosphate (cGMP), were measured. Diagnosis of simple schizophrenia, slow first remission, poor intermorbid adjustment, young age of onset, and absence of hallucinations are all significantly associated with increasing CSF cAMP. CSF cGMP was not significantly correlated with any clinical variable.",

author = "J. Zohar and J. Biederman and R. Rimon and R. Ebstein and Belmaker, \{R. H.\}",

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AU - Zohar, J.

AU - Biederman, J.

AU - Rimon, R.

AU - Ebstein, R.

AU - Belmaker, R. H.

PY - 1978/1/1

Y1 - 1978/1/1

N2 - The patient group consisted of 20 consecutive admissions of drug-free schizophrenic patients. Lumbar CSF was obtained and cyclic nucleotides, cAMP and cyclic guanosine monophosphate (cGMP), were measured. Diagnosis of simple schizophrenia, slow first remission, poor intermorbid adjustment, young age of onset, and absence of hallucinations are all significantly associated with increasing CSF cAMP. CSF cGMP was not significantly correlated with any clinical variable.

AB - The patient group consisted of 20 consecutive admissions of drug-free schizophrenic patients. Lumbar CSF was obtained and cyclic nucleotides, cAMP and cyclic guanosine monophosphate (cGMP), were measured. Diagnosis of simple schizophrenia, slow first remission, poor intermorbid adjustment, young age of onset, and absence of hallucinations are all significantly associated with increasing CSF cAMP. CSF cGMP was not significantly correlated with any clinical variable.

UR - https://www.scopus.com/pages/publications/0017891505

U2 - 10.1176/ajp.135.2.253

DO - 10.1176/ajp.135.2.253

M3 - Article

AN - SCOPUS:0017891505

SN - 0002-953X

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SP - 253

EP - 255

JO - American Journal of Psychiatry

JF - American Journal of Psychiatry

IS - 2

ER -

Clinical correlates of CSF cyclic nucleotides in schizophrenia

Abstract

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