Clinical results of drug eluting stents compared to bare metal stents for patients with ST elevation acute myocardial infarction

R. Kornowski, H. Vaknin-Assa, E. Lev, I. Ben-Dor, I. Teplitsky, E. Rechavia, D. Brosh, S. Fuchs, A. Assali

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations

    Abstract

    Objective: To investigate the clinical outcomes in patients with ST segment elevation acute myocardial infarction (STEMI) treated with drug eluting stents (DES) versus a matched control group of patients with STEMI treated with bare metal stents (BMS). Methods: This registry included 122 patients with STEMI undergoing primary coronary angioplasty with DES implantation at our institution. The control group consisted of 506 patients implanted with BMS, who were matched for age, infarct location, and diabetic status. The incidences of major adverse cardiac events (MACE) including target vessel/lesion revascularization (TVR/TLR) and stent thrombosis were assessed up to 12 months. Results: Twelve months follow up showed a non-significant trend towards reduced deaths (3.3% versus 7.1%, P=0.1), significantly reduced recurrent MI (0.0% versus 6.1%, P=0.02), TVR (5.7% versus 15.2%, P=0.006) and TLR (2.5% versus 14.0%, P=0.004) events in the DES group as compared to BMS group. The composite incidences of MACE at 12 months follow-up was lower in the DES group (11.5%) as compared to the BMS group (21.3%, P=0.01). Conclusion: According to our experiences, the use of DES in STEMI is safe and effective as compared to BMS. DES was effective in reducing the incidence of restenosis outcomes and overall adverse cardiac events up to 12 months.

    Original languageEnglish
    Pages (from-to)167-172
    Number of pages6
    JournalAcute Cardiac Care
    Volume10
    Issue number3
    DOIs
    StatePublished - 30 Sep 2008

    Keywords

    • Acute myocardial infarction
    • Angioplasty
    • DES
    • Paclitaxel-eluting stents
    • Sirolimus-eluting stent

    ASJC Scopus subject areas

    • Emergency Medicine
    • Radiology Nuclear Medicine and imaging
    • Cardiology and Cardiovascular Medicine

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