TY - JOUR
T1 - Clinical validation of a wearable respiratory rate device
T2 - A brief report
AU - Eisenkraft, Arik
AU - Goldstein, Nir
AU - Ben Ishay, Arik
AU - Fons, Meir
AU - Tabi, Michael
AU - Sherman, Anna Danielle
AU - Merin, Roei
AU - Nachman, Dean
N1 - Publisher Copyright:
© The Author(s) 2023.
PY - 2023/1/1
Y1 - 2023/1/1
N2 - Background: Respiratory rate (RR) is used for the diagnosis and management of medical conditions and can predict clinical changes. Heavy workload, understaffing, and errors related to poor recording make it underutilized. Wearable devices may facilitate its use. Methods: RR measurements using a wearable photoplethysmography-based monitor were compared with medical grade devices in complementary clinical scenarios: Study one included a comparison to a capnograph in 35 healthy volunteers; Study two included a comparison to a ventilator monitor in 18 ventilated patients; and Study three included a comparison to capnograph in 92 COVID-19 patients with active pulmonary disease. Pearson’s correlations and Bland-Altman analysis were used to assess the accuracy and agreement between the measurement techniques, including stratification for Body Mass Index (BMI) and skin tone. Statistical significance was set at p ≤ 0.05. Results: High correlation was found in all studies (r = 0.991, 0.884, and 0.888, respectively, p < 0.001 for all). 95% LOA of ±2.3, 1.7-(−1.6), and ±3.9 with a bias of < 0.1 breaths per minute was found in Bland-Altman analysis in studies 1,2, and 3, respectively. In all, high accordance was found in all sub-groups. Conclusions: RR measurements using the wearable monitor were highly-correlated with medical-grade devices in various clinical settings. Trial registration: ClinicalTrials.gov, https://clinicaltrials.gov/ct2/show/NCT03603860.
AB - Background: Respiratory rate (RR) is used for the diagnosis and management of medical conditions and can predict clinical changes. Heavy workload, understaffing, and errors related to poor recording make it underutilized. Wearable devices may facilitate its use. Methods: RR measurements using a wearable photoplethysmography-based monitor were compared with medical grade devices in complementary clinical scenarios: Study one included a comparison to a capnograph in 35 healthy volunteers; Study two included a comparison to a ventilator monitor in 18 ventilated patients; and Study three included a comparison to capnograph in 92 COVID-19 patients with active pulmonary disease. Pearson’s correlations and Bland-Altman analysis were used to assess the accuracy and agreement between the measurement techniques, including stratification for Body Mass Index (BMI) and skin tone. Statistical significance was set at p ≤ 0.05. Results: High correlation was found in all studies (r = 0.991, 0.884, and 0.888, respectively, p < 0.001 for all). 95% LOA of ±2.3, 1.7-(−1.6), and ±3.9 with a bias of < 0.1 breaths per minute was found in Bland-Altman analysis in studies 1,2, and 3, respectively. In all, high accordance was found in all sub-groups. Conclusions: RR measurements using the wearable monitor were highly-correlated with medical-grade devices in various clinical settings. Trial registration: ClinicalTrials.gov, https://clinicaltrials.gov/ct2/show/NCT03603860.
KW - Remote patient monitoring
KW - breaths per minute
KW - comparative study
KW - continuous monitoring
KW - respiratory rate
UR - https://www.scopus.com/pages/publications/85168595658
U2 - 10.1177/14799731231198865
DO - 10.1177/14799731231198865
M3 - Article
C2 - 37612250
AN - SCOPUS:85168595658
SN - 1479-9723
VL - 20
JO - Chronic Respiratory Disease
JF - Chronic Respiratory Disease
ER -