Coeliac disease associated with psoriasis

S. Birkenfeld, J. Dreiher, D. Weitzman, A. D. Cohen

Research output: Contribution to journalArticlepeer-review

87 Scopus citations


Background Psoriasis is a chronic inflammatory disorder of the skin reported to be associated with systemic comorbidities. Objectives To investigate the association between psoriasis and coeliac disease (CD). Methods Patients with psoriasis were compared with age- and sex-matched controls regarding the prevalence of CD in a case-control study. χ2 and t-tests were used for univariate analysis and a logistic regression model was used for multivariate analysis. The study was performed utilizing the medical database of Clalit Health Services. Results The study included 12 502 patients with psoriasis aged > 20 years and 24 285 age- and sex-matched controls. The prevalence of CD in patients with psoriasis was increased compared with the prevalence in controls (0·29% and 0·11%, respectively, P < 0·001). In a multivariate analysis psoriasis was associated with CD (odds ratio 2·73, 95% confidence interval 1·65-4·53). Conclusions Patients with psoriasis have a greater prevalence of CD than matched controls. Recent studies showed a possibility of undiagnosed CD among patients with psoriasis. Therefore, physicians treating patients with psoriasis should be aware of this possible association.

Original languageEnglish
Pages (from-to)1331-1334
Number of pages4
JournalBritish Journal of Dermatology
Issue number6
StatePublished - 1 Dec 2009


  • Coeliac disease
  • Coeliac sprue
  • Comorbidity
  • Gluten-sensitive enteropathy
  • Psoriasis

ASJC Scopus subject areas

  • Dermatology


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