Comparative study of the antioxidant and reactive oxygen species scavenging properties in the extracts of the fruits of Terminalia chebula, Terminalia belerica, and emblica officinalis

Bibhabasu Hazra, Rhitajit Sarkar, Santanu Biswas, Nripendranath Mandal

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Oxidative stress plays an important role in the pathogenesis of various diseases such as atherosclerosis, alcoholic liver cirrhosis and cancer etc. Oxidative stress is initiated by reactive oxygen species (ROS), such as superoxide anion (O-2), perhydroxy radical (HOO-) and hydroxyl radical (HO·). These radicals are formed by a one electron reduction process of molecular oxygen (O2). ROS can easily initiate the lipid peroxidation of the membrane lipids, causing damage of the cell membrane of phospholipids, lipoprotein by propagating a chain reaction cycle [1,2]. Thus, antioxidants defense systems have coevolved with aerobic metabolism to counteract oxidative damage from ROS. Most living species have efficient defense systems to prevent themselves against oxidative stress induced by ROS [3]. Recent investigations have shown that the antioxidant properties of plants could be correlated with oxidative stress defense and different human diseases and aging process etc [4]. In this respect flavonoids and other polyphenolic compounds have received the greatest attention.

Original languageEnglish
Title of host publicationRecent Advances in Plant-Based, Traditional, and Natural Medicines
PublisherApple Academic Press
Pages181-214
Number of pages34
ISBN (Electronic)9781482243598
ISBN (Print)9781771880138
StatePublished - 1 Jan 2014
Externally publishedYes

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