Complete sequence and organization of pBtoxis, the toxin-coding plasmid of Bacillus thuringiensis subsp. israelensis

Colin Berry, Susan O'Neil, Eitan Ben-Dov, Andrew F. Jones, Lee Murphy, Michael A. Quail, Mathew T.G. Holden, David Harris, Arieh Zaritsky, Julian Parkhill

Research output: Contribution to journalArticlepeer-review

242 Scopus citations

Abstract

The entire 127,923-bp sequence of the toxin-encoding plasmid pBtoxis from Bacillus thuringiensis subsp. israelensis is presented and analyzed. In addition to the four known Cry and two known Cyt toxins, a third Cyt-type sequence was found with an additional C-terminal domain previously unseen in such proteins. Many plasmid-encoded genes could be involved in several functions other than toxin production. The most striking of these are several genes potentially affecting host sporulation and germination and a set of genes for the production and export of a peptide antibiotic.

Original languageEnglish
Pages (from-to)5082-5095
Number of pages14
JournalApplied and Environmental Microbiology
Volume68
Issue number10
DOIs
StatePublished - 1 Oct 2002
Externally publishedYes

ASJC Scopus subject areas

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology
  • Ecology

Fingerprint

Dive into the research topics of 'Complete sequence and organization of pBtoxis, the toxin-coding plasmid of Bacillus thuringiensis subsp. israelensis'. Together they form a unique fingerprint.

Cite this