Abstract
Complicated otitis media (OM) is a common paediatric problem and includes two major entities: persistent acute OM (AOM) and recurrent AOM (R-AOM). Double-tympanocentesis studies comparing the microbiology of initial and recurrent episodes of AOM have demonstrated that most recurrent episodes occurring within 1 month after antibiotic therapy are new infections, not true bacteriological relapses. These findings have highlighted the importance of bacteriological eradication in the prevention of subsequent R-AOM episodes. The seven-valent pneumococcal conjugate vaccine (PCV7) targets Streptococcus pneumoniae, one of the main AOM pathogens, and data on the impact of PCV7 on complications of AOM, such as mastoiditis, are presented.
| Original language | English |
|---|---|
| Pages (from-to) | G16-G19 |
| Journal | Vaccine |
| Volume | 26 |
| Issue number | SUPPL. 7 |
| DOIs | |
| State | Published - 23 Dec 2008 |
Keywords
- Mastoiditis
- Persistent otitis media
- Recurrent otitis media
ASJC Scopus subject areas
- Molecular Medicine
- General Immunology and Microbiology
- General Veterinary
- Public Health, Environmental and Occupational Health
- Infectious Diseases