Composite nasopharyngeal plasmacytoma with nodal paraimmunoblastic variant of small lymphocytic lymphoma: A case report

Karen Nalbandyan, Daniel Benharroch, Ory Rouvio, Anna Gurevitch

Research output: Contribution to journalArticlepeer-review

Abstract

A 78-year-old male who presented with severe shortness of breath and bilateral nasal congestion was shown to exhibit ta mass localized in the nasopharynx. The tumor was diagnosed as an extramedullary plasmacytoma. Periph­eral blood eosinophilia had been persistently noted in the preceding 12 years. The plasmacytoma exhibited a predomi­nance of κ-light chain monotypic Mott cells and was admixed with numerous eosinophils. No history of allergic rhinitis, asthma or aspirin sensitivity was elicited. An axillary lymph node was excised two weeks after the nasopharyngeal biopsy, and it exhibited a paraimmunoblastic transformation of small lymphocytic lymphoma. A review of the literature identified few occurrences of such simultaneous tumors in individual patients.

Original languageEnglish
Pages (from-to)1745-1747
Number of pages3
JournalOncology Letters
Volume14
Issue number2
DOIs
StatePublished - 1 Jan 2017

Keywords

  • Paraimmunoblastic transformation of small lymphocytic lymphoma
  • Plasmacytoma
  • Synchronous

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