Compositions and Methods Related to Graft Versus Host Disease and Treatments Thereof

Leland Shapiro (Inventor), Eli C Lewis (Inventor), Charles A Dinarello (Inventor)

Research output: Patent

Abstract

Embodiments of the present invention illustrate methods of treating and preventing transplantation and side effects associated with transplantation. In particular, the present invention relates to compositions and methods for inhibition of graft rejection and promotion of graft survival. Thus, the invention relates to modulation of cellular activities, including graft rejection, promotion of graft survival, graft versus host rejection and conditions commonly associated with graft rejection. More particularly, the present invention relates to the inhibitory compounds comprising naturally occurring and man-made inhibitors of serine protease and inducers of other alpha1-antitrypsin activities.
Original languageEnglish
Patent numberUS20180133294A1
StatePublished - 1 May 2018

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