TY - JOUR
T1 - Computerized respiratory muscle training in children with Duchenne muscular dystrophy
AU - Vilozni, Daphna
AU - Bar-Yishay, Ephraim
AU - Gur, Ilan
AU - Shapira, Yehuda
AU - Meyer, Shirley
AU - Godfrey, Simon
N1 - Funding Information:
Acknowledgements--This study was supported in part by grants from the Muscular Dystrophy Association (New York, NY, U.S.A.), the Israeli Ministry of Health, Jerusalem, and by Alyn Children's Orthopedic Hospital, Jerusalem, Israel.
PY - 1994/1/1
Y1 - 1994/1/1
N2 - The present study describes the use of simple video games for a 5-week regimen of respiratory muscle training in 15 patients with Duchenne muscular dystrophy (DMD) at various stages of the disease. The games were re-arranged to be operated and driven by the respiratory efforts of the patient and to incorporate accurate ventilation and time measurements. Improvement in respiratory performance was determined by maximum voluntary ventilation (MVV), maximal achieved ventilation (VEmax) during a progressive isocapnic hyperventilation manoeuvre (PIHV) and the PIHV duration. The actual training period was 23 ± 4 days (mean ±S.D.) at ventilatory effort of 46 ± 6% MVV, for 10±3 min day-1. Patients with moderate impairment of lung function tests (LFT) showed an improvement in MVV, V Emax, and duration of PIHV of 12 ± 7% (p < 0.02), 53 ± 25% (p < 0.001) 57 ± 21% (p < 0.01), respectively. Improvements correlated with actual training time and ventilation level, %MVV, but negatively correlated with years of immobilization and with the initial MVV. We conclude that computerized respiratory games may be applied for breathing exercises and may improve respiratory performance in recently immobilized children with DMD who have moderate impairment of LFT.
AB - The present study describes the use of simple video games for a 5-week regimen of respiratory muscle training in 15 patients with Duchenne muscular dystrophy (DMD) at various stages of the disease. The games were re-arranged to be operated and driven by the respiratory efforts of the patient and to incorporate accurate ventilation and time measurements. Improvement in respiratory performance was determined by maximum voluntary ventilation (MVV), maximal achieved ventilation (VEmax) during a progressive isocapnic hyperventilation manoeuvre (PIHV) and the PIHV duration. The actual training period was 23 ± 4 days (mean ±S.D.) at ventilatory effort of 46 ± 6% MVV, for 10±3 min day-1. Patients with moderate impairment of lung function tests (LFT) showed an improvement in MVV, V Emax, and duration of PIHV of 12 ± 7% (p < 0.02), 53 ± 25% (p < 0.001) 57 ± 21% (p < 0.01), respectively. Improvements correlated with actual training time and ventilation level, %MVV, but negatively correlated with years of immobilization and with the initial MVV. We conclude that computerized respiratory games may be applied for breathing exercises and may improve respiratory performance in recently immobilized children with DMD who have moderate impairment of LFT.
KW - Duchenne muscular dystrophy
KW - Respiratory muscle training
KW - computerized games
UR - http://www.scopus.com/inward/record.url?scp=0028358172&partnerID=8YFLogxK
U2 - 10.1016/0960-8966(94)90026-4
DO - 10.1016/0960-8966(94)90026-4
M3 - Article
C2 - 7919973
AN - SCOPUS:0028358172
VL - 4
SP - 249
EP - 255
JO - Neuromuscular Disorders
JF - Neuromuscular Disorders
SN - 0960-8966
IS - 3
ER -