Computerized respiratory muscle training in children with Duchenne muscular dystrophy

Daphna Vilozni, Ephraim Bar-Yishay, Ilan Gur, Yehuda Shapira, Shirley Meyer, Simon Godfrey

Research output: Contribution to journalArticlepeer-review

50 Scopus citations


The present study describes the use of simple video games for a 5-week regimen of respiratory muscle training in 15 patients with Duchenne muscular dystrophy (DMD) at various stages of the disease. The games were re-arranged to be operated and driven by the respiratory efforts of the patient and to incorporate accurate ventilation and time measurements. Improvement in respiratory performance was determined by maximum voluntary ventilation (MVV), maximal achieved ventilation (VEmax) during a progressive isocapnic hyperventilation manoeuvre (PIHV) and the PIHV duration. The actual training period was 23 ± 4 days (mean ±S.D.) at ventilatory effort of 46 ± 6% MVV, for 10±3 min day-1. Patients with moderate impairment of lung function tests (LFT) showed an improvement in MVV, V Emax, and duration of PIHV of 12 ± 7% (p < 0.02), 53 ± 25% (p < 0.001) 57 ± 21% (p < 0.01), respectively. Improvements correlated with actual training time and ventilation level, %MVV, but negatively correlated with years of immobilization and with the initial MVV. We conclude that computerized respiratory games may be applied for breathing exercises and may improve respiratory performance in recently immobilized children with DMD who have moderate impairment of LFT.

Original languageEnglish
Pages (from-to)249-255
Number of pages7
JournalNeuromuscular Disorders
Issue number3
StatePublished - 1 Jan 1994
Externally publishedYes


  • Duchenne muscular dystrophy
  • Respiratory muscle training
  • computerized games

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Clinical Neurology
  • Genetics(clinical)


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