Concerted 2-5A-Mediated mRNA Decay and Transcription Reprogram Protein Synthesis in the dsRNA Response

Biochemistry, Genetics and Molecular Biology

• Transcription 100%
• Messenger RNA 100%
• Protein Biosynthesis 100%
• Translation Initiation 100%
• Double-Stranded RNA 100%
• Ribonuclease L 100%
• Interferon 100%
• Homeostasis 50%
• RNA Sequence 50%
• Spike 50%
• Mammalian Cell 50%
• Positive Feedback 50%
• Polysome 50%
• Initiation Complex 50%
• RNA Degradation 50%

Keyphrases

• 2-5A 100%
• Protein Synthesis 100%
• MRNA Decay 100%
• Double-stranded RNA 100%
• RNA Transcription 100%
• Innate Immune Response 33%
• Immune Proteins 33%
• RNase L 33%
• Homeostasis 16%
• Viral 16%
• Mammalian Cells 16%
• RNA Sequencing (RNA-seq) 16%
• Interferon-α (IFN-α) 16%
• Stress Response 16%
• Human Cells 16%
• Polysome 16%
• Positive Feedback 16%
• Translation Initiation 16%
• Response Switching 16%
• Spike-in 16%
• RNA Degradation 16%
• Translation Initiation Complex 16%
• Interferon Response 16%
• Collapse Pattern 16%

Immunology and Microbiology

• Protein Synthesis 100%
• Interferon 100%
• Translation Initiation 100%
• Ribonuclease L 100%
• Spike 50%
• RNA Sequence 50%
• Positive Feedback 50%
• Human Cell 50%
• Homeostasis 50%
• Polysome 50%
• Ribosome 50%
• RNA Degradation 50%