Conformers of guanosines and their vibrations in the electronic ground and excited states, as revealed by double-resonance spectroscopy and ab initio calculations

Eyal Nir, Isabel Hünig, Karl Kleinermanns, Mattanjah S. De Vries

Research output: Contribution to journalArticlepeer-review

53 Scopus citations

Abstract

Strong intramolecular 5′-OH ⋯ 3-N hydrogen bonds stabilize guanosine, 2′-deoxyguanosine, and 3′-deoxyguanosine and fold them into a single preferred conformation (see picture), even in the absence of solvent interactions or DNA backbones. This conclusion was reached by means of a study combining UV-UV and IR-UV double-resonance laser spectroscopy and ab initio calculations.

Original languageEnglish
Pages (from-to)131-137
Number of pages7
JournalChemPhysChem
Volume5
Issue number1
DOIs
StatePublished - 23 Jan 2004
Externally publishedYes

Keywords

  • Ab initio calculations
  • IR spectroscopy
  • Laser spectroscopy
  • Nucleosides UV/Vis spectroscopy

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Physical and Theoretical Chemistry

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