TY - JOUR
T1 - Congenital Pulmonary Hybrid Lesions
T2 - Clinical Presentation, Surgical Management, and Outcomes
AU - Gatt, Dvir
AU - Lapidus-Krol, Eveline
AU - Chiu, Priscilla P.L.
N1 - Publisher Copyright:
© The Author(s), under exclusive licence to Dr. K C Chaudhuri Foundation 2025.
PY - 2025/12/1
Y1 - 2025/12/1
N2 - Objectives: Congenital pulmonary airway malformation (CPAM) lesion with an aberrant systemic blood supply is considered a “hybrid” lesion (HL). The aim of the study was to report authors’ experience in the presentation, surgical management, and outcomes of HL. Methods: A retrospective cohort study of HL patients followed from 2000 to 2022 in a single institution was done. Clinical and radiographic data were collected from the medical records. Results: Over the study period, 39 patients with HL were identified. HL with CPAM type 2 was more common than type 1 (74% vs. 26%), and intralobar sequestrations were more prevalent than extralobar sequestrations (ELS) (79.5% vs. 20.5%). HL with CPAM type 2 had higher rates of co-morbidities and higher likelihood to present with respiratory symptoms after birth. HL with ELS had smaller feeding vessels (all < 4 mm) which resulted in lower rates of open thoracotomy approach for resection. Conclusions: The variability in HL patient presentation and outcomes is correlated with the size and the hybrid composition.
AB - Objectives: Congenital pulmonary airway malformation (CPAM) lesion with an aberrant systemic blood supply is considered a “hybrid” lesion (HL). The aim of the study was to report authors’ experience in the presentation, surgical management, and outcomes of HL. Methods: A retrospective cohort study of HL patients followed from 2000 to 2022 in a single institution was done. Clinical and radiographic data were collected from the medical records. Results: Over the study period, 39 patients with HL were identified. HL with CPAM type 2 was more common than type 1 (74% vs. 26%), and intralobar sequestrations were more prevalent than extralobar sequestrations (ELS) (79.5% vs. 20.5%). HL with CPAM type 2 had higher rates of co-morbidities and higher likelihood to present with respiratory symptoms after birth. HL with ELS had smaller feeding vessels (all < 4 mm) which resulted in lower rates of open thoracotomy approach for resection. Conclusions: The variability in HL patient presentation and outcomes is correlated with the size and the hybrid composition.
KW - BPS
KW - CCAM
KW - CPAM
KW - Congenital lung malformation
KW - Feeding vessel
UR - https://www.scopus.com/pages/publications/85217269183
U2 - 10.1007/s12098-024-05393-7
DO - 10.1007/s12098-024-05393-7
M3 - Article
C2 - 39833625
AN - SCOPUS:85217269183
SN - 0019-5456
VL - 92
SP - 1296
EP - 1301
JO - Indian Journal of Pediatrics
JF - Indian Journal of Pediatrics
IS - 12
ER -