Control of network output by synaptic depression

Farzan Nadim, Yair Manor, Amitabha Bose

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


In a network of an excitatory and an inhibitory neuron, depression in the inhibitory synapse can produce two distinct oscillatory regimes. In one regime, the network has a short period cell-dominated solution; in the other regime, the solution has much longer period and is synapse-dominated. These regimes overlap to produce an interval of bistability. Neuromodulatory input that targets one of multiple parameters in the network can switch the network control between the intrinsic properties of cells and the dynamics of the synapses.

Original languageEnglish
Pages (from-to)781-787
Number of pages7
StatePublished - 1 Jun 2001


  • Bistability
  • Inhibition
  • Oscillations

ASJC Scopus subject areas

  • Computer Science Applications
  • Cognitive Neuroscience
  • Artificial Intelligence


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