Coordinate induction of glutathione biosynthesis and glutathione- metabolizing enzymes is correlated with salt tolerance in tomato

Valentina Mittova, Frederica L. Theodoulou, Guy Kiddle, Leonardo Gómez, Micha Volokita, Moshe Tal, Christine H. Foyer, Micha Guy

Research output: Contribution to journalArticlepeer-review

112 Scopus citations

Abstract

The acclimation of reduced glutathione (GSH) biosynthesis and GSH-utilizing enzymes to salt stress was studied in two tomato species that differ in stress tolerance. Salt increased GSH content and GSH:GSSG (oxidized glutathione) ratio in oxidative stress-tolerant Lycopersicon pennellii (Lpa) but not in Lycopersicon esculentum (Lem). These changes were associated with salt-induced upregulation of γ-glutamylcysteine synthetase protein, an effect which was prevented by preincubation with buthionine sulfoximine. Salt treatment induced glutathione peroxidase and glutathione-S-transferase but not glutathione reductase activities in Lpa. These results suggest a mechanism of coordinate upregulation of synthesis and metabolism of GSH in Lpa, that is absent from Lem.

Original languageEnglish
Pages (from-to)417-421
Number of pages5
JournalFEBS Letters
Volume554
Issue number3
DOIs
StatePublished - 20 Nov 2003

Keywords

  • Glutathione
  • Glutathione peroxidase
  • Glutathione-S-transferase
  • Salt tolerance
  • Tomato
  • γ-Glutamylcysteine synthetase

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