Correlations between clusters of protein-DNA binding sites and the binding experimental data allow predicting a structure of regulatory modules

A. A. Nikulova; M. S. Polishchuk; V. G. Tumanian; V. Yu Makeev; A. A. Mironov; A. V. Favorov

doi:10.1134/S0006350912020157

Correlations between clusters of protein-DNA binding sites and the binding experimental data allow predicting a structure of regulatory modules

A. A. Nikulova, M. S. Polishchuk, V. G. Tumanian, V. Yu Makeev, A. A. Mironov, A. V. Favorov

Research output: Contribution to journal › Article › peer-review

Abstract

Here we analyzed an option to predict the structure of cis-regulatory modules that consist of binding sites of different proteins (heterogeneous cis-regulatory modules) using mutual positional correlations between protein-DNA binding experimental data and computationally identified clusters of binding sites for each of the proteins.

Original language	English
Pages (from-to)	138-139
Number of pages	2
Journal	Biophysics (Russian Federation)
Volume	57
Issue number	2
DOIs	https://doi.org/10.1134/S0006350912020157
State	Published - 1 Mar 2012
Externally published	Yes

Keywords

CORE-CLUST
CRM
ChIP-Seq
ChIP-chip
GenometriCorr
PatternClust
binding site cluster
cis-regulatory module

ASJC Scopus subject areas

Biophysics

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10.1134/S0006350912020157

Cite this

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title = "Correlations between clusters of protein-DNA binding sites and the binding experimental data allow predicting a structure of regulatory modules",

abstract = "Here we analyzed an option to predict the structure of cis-regulatory modules that consist of binding sites of different proteins (heterogeneous cis-regulatory modules) using mutual positional correlations between protein-DNA binding experimental data and computationally identified clusters of binding sites for each of the proteins.",

keywords = "CORE-CLUST, CRM, ChIP-Seq, ChIP-chip, GenometriCorr, PatternClust, binding site cluster, cis-regulatory module",

author = "Nikulova, \{A. A.\} and Polishchuk, \{M. S.\} and Tumanian, \{V. G.\} and Makeev, \{V. Yu\} and Mironov, \{A. A.\} and Favorov, \{A. V.\}",

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T1 - Correlations between clusters of protein-DNA binding sites and the binding experimental data allow predicting a structure of regulatory modules

AU - Nikulova, A. A.

AU - Polishchuk, M. S.

AU - Tumanian, V. G.

AU - Makeev, V. Yu

AU - Mironov, A. A.

AU - Favorov, A. V.

PY - 2012/3/1

Y1 - 2012/3/1

N2 - Here we analyzed an option to predict the structure of cis-regulatory modules that consist of binding sites of different proteins (heterogeneous cis-regulatory modules) using mutual positional correlations between protein-DNA binding experimental data and computationally identified clusters of binding sites for each of the proteins.

AB - Here we analyzed an option to predict the structure of cis-regulatory modules that consist of binding sites of different proteins (heterogeneous cis-regulatory modules) using mutual positional correlations between protein-DNA binding experimental data and computationally identified clusters of binding sites for each of the proteins.

KW - CORE-CLUST

KW - CRM

KW - ChIP-Seq

KW - ChIP-chip

KW - GenometriCorr

KW - PatternClust

KW - binding site cluster

KW - cis-regulatory module

UR - https://www.scopus.com/pages/publications/84863097269

U2 - 10.1134/S0006350912020157

DO - 10.1134/S0006350912020157

M3 - Article

AN - SCOPUS:84863097269

SN - 0006-3509

VL - 57

SP - 138

EP - 139

JO - Biophysics (Russian Federation)

JF - Biophysics (Russian Federation)

IS - 2

ER -

Correlations between clusters of protein-DNA binding sites and the binding experimental data allow predicting a structure of regulatory modules

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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