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Correlations between clusters of protein-DNA binding sites and the binding experimental data allow predicting a structure of regulatory modules

  • A. A. Nikulova
  • , M. S. Polishchuk
  • , V. G. Tumanian
  • , V. Yu Makeev
  • , A. A. Mironov
  • , A. V. Favorov

Research output: Contribution to journalArticlepeer-review

Abstract

Here we analyzed an option to predict the structure of cis-regulatory modules that consist of binding sites of different proteins (heterogeneous cis-regulatory modules) using mutual positional correlations between protein-DNA binding experimental data and computationally identified clusters of binding sites for each of the proteins.

Original languageEnglish
Pages (from-to)138-139
Number of pages2
JournalBiophysics (Russian Federation)
Volume57
Issue number2
DOIs
StatePublished - 1 Mar 2012
Externally publishedYes

Keywords

  • CORE-CLUST
  • CRM
  • ChIP-Seq
  • ChIP-chip
  • GenometriCorr
  • PatternClust
  • binding site cluster
  • cis-regulatory module

ASJC Scopus subject areas

  • Biophysics

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