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Correlative interrelations between the oxygen consumption rate, body temperature and activities of the key antioxidant enzymes of liver of Mus musculus

  • Kh K. Muradian
  • , N. A. Utko
  • , T. G. Mozzhukhina
  • , I. N. Pishel
  • , A. Ya Litoshenko
  • , V. V. Bezrukov
  • , V. E. Fraifeld

Research output: Contribution to journalArticlepeer-review

Abstract

Using one-, two-, and three-dimensional statistical methods, there were analyzed peculiarities of distribution and the degree of the correlative-regressional dependence between the parameters characterizing the oxygen consumption rate (V O2), body temperature (BT), activities of three key enzymes of the antioxidant system - superoxide dismutase (SOD), catalase (CL), and glutathion peroxidase (GP) in 15 females of the laboratory population of Mus musculus. The performed studies have shown that the three-dimensional non-linear models better correspond to the actual data and clearly demonstrate specificity of the antioxidant enzymes, as regulatory targets. Changes of the SOD and CL activities depend mainly on V O2, whereas GP can be the target equally accessible for the regulatory factors of oxidative processes and thermoregulation.

Original languageEnglish
Pages (from-to)62-65
Number of pages4
JournalJournal of Evolutionary Biochemistry and Physiology
Volume40
Issue number1
DOIs
StatePublished - 1 Jan 2004

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Biochemistry
  • Physiology

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