COVID-19 and assisted reproductive technology services: Repercussions for patients and proposal for individualized clinical management

Carlo Alviggi, Sandro C. Esteves, Raoul Orvieto, Alessandro Conforti, Antonio La Marca, Robert Fischer, Claus Y. Andersen, Klaus Bühler, Sesh K. Sunkara, Nikolaos P. Polyzos, Ida Strina, Luigi Carbone, Fabiola C. Bento, Daniela Galliano, Hakan Yarali, Lan N. Vuong, Michael Grynberg, Panagiotis Drakopoulos, Pedro Xavier, Joaquin LlacerFernando Neuspiller, Marcos Horton, Matheus Roque, Evangelos Papanikolaou, Manish Banker, Michael H. Dahan, Shu Foong, Herman Tournaye, Christophe Blockeel, Alberto Vaiarelli, Peter Humaidan, Filippo M. Ubaldi

Research output: Contribution to journalReview articlepeer-review

50 Scopus citations


The prolonged lockdown of health services providing high-complexity fertility treatments -as currently recommended by many reproductive medicine entities- is detrimental for society as a whole, and infertility patients in particular. Globally, approximately 0.3% of all infants born every year are conceived using assisted reproductive technology (ART) treatments. By contrast, the total number of COVID-19 deaths reported so far represents approximately 1.0% of the total deaths expected to occur worldwide over the first three months of the current year. It seems, therefore, that the number of infants expected to be conceived and born -but who will not be so due to the lockdown of infertility services- might be as significant as the total number of deaths attributed to the COVID-19 pandemic. We herein propose remedies that include a prognostic-stratification of more vulnerable infertility cases in order to plan a progressive restart of worldwide fertility treatments. At a time when preventing complications and limiting burdens for national health systems represent relevant issues, our viewpoint might help competent authorities and health care providers to identify patients who should be prioritized for the continuation of fertility care in a safe environment.

Original languageEnglish
Article number45
JournalReproductive Biology and Endocrinology
Issue number1
StatePublished - 13 May 2020
Externally publishedYes


  • Assisted reproductive technology
  • COVID-19
  • In vitro fertilization
  • Infertility
  • Intracytoplasmic sperm injection
  • Poseidon criteria
  • Viewpoint

ASJC Scopus subject areas

  • Reproductive Medicine
  • Endocrinology
  • Obstetrics and Gynecology
  • Developmental Biology


Dive into the research topics of 'COVID-19 and assisted reproductive technology services: Repercussions for patients and proposal for individualized clinical management'. Together they form a unique fingerprint.

Cite this