CSF inositol does not predict antidepressant response to inositol

J. Levine; L. Kurtzman; A. Rapoport; J. Zimmerman; Y. Bersudsky; J. Shapiro; R. H. Belmaker; G. Agam

doi:10.1007/BF01271260

CSF inositol does not predict antidepressant response to inositol

J. Levine, L. Kurtzman, A. Rapoport, J. Zimmerman, Y. Bersudsky, J. Shapiro, R. H. Belmaker, G. Agam

Department of Clinical Biochemistry and Pharmacology

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

CSF inositol was reported to be reduced in depression and inositol has been reported to be effective in treatment of depression. We studied CSF inositol in 18 drug-free depressed patients and 36 normal controls; the depressed patients then participated in an open trial of 18 gm daily inositol treatment for 4 weeks. There was no difference in pre-treatment CSF inositol between depressed patients and controls. CSF inositol levels did not predict response on the Hamilton Depression Scale to 4 weeks of inositol treatment.

Original language	English
Pages (from-to)	1457-1462
Number of pages	6
Journal	Journal of Neural Transmission
Volume	103
Issue number	12
DOIs	https://doi.org/10.1007/BF01271260
State	Published - 1 Dec 1996

Keywords

CSF
Depression
Inositol

ASJC Scopus subject areas

Neurology
Clinical Neurology
Psychiatry and Mental health
Biological Psychiatry

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10.1007/BF01271260

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title = "CSF inositol does not predict antidepressant response to inositol",

abstract = "CSF inositol was reported to be reduced in depression and inositol has been reported to be effective in treatment of depression. We studied CSF inositol in 18 drug-free depressed patients and 36 normal controls; the depressed patients then participated in an open trial of 18 gm daily inositol treatment for 4 weeks. There was no difference in pre-treatment CSF inositol between depressed patients and controls. CSF inositol levels did not predict response on the Hamilton Depression Scale to 4 weeks of inositol treatment.",

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author = "J. Levine and L. Kurtzman and A. Rapoport and J. Zimmerman and Y. Bersudsky and J. Shapiro and Belmaker, {R. H.} and G. Agam",

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AU - Levine, J.

AU - Kurtzman, L.

AU - Rapoport, A.

AU - Zimmerman, J.

AU - Bersudsky, Y.

AU - Shapiro, J.

AU - Belmaker, R. H.

AU - Agam, G.

PY - 1996/12/1

Y1 - 1996/12/1

N2 - CSF inositol was reported to be reduced in depression and inositol has been reported to be effective in treatment of depression. We studied CSF inositol in 18 drug-free depressed patients and 36 normal controls; the depressed patients then participated in an open trial of 18 gm daily inositol treatment for 4 weeks. There was no difference in pre-treatment CSF inositol between depressed patients and controls. CSF inositol levels did not predict response on the Hamilton Depression Scale to 4 weeks of inositol treatment.

AB - CSF inositol was reported to be reduced in depression and inositol has been reported to be effective in treatment of depression. We studied CSF inositol in 18 drug-free depressed patients and 36 normal controls; the depressed patients then participated in an open trial of 18 gm daily inositol treatment for 4 weeks. There was no difference in pre-treatment CSF inositol between depressed patients and controls. CSF inositol levels did not predict response on the Hamilton Depression Scale to 4 weeks of inositol treatment.

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KW - Depression

KW - Inositol

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JO - Journal of Neural Transmission

JF - Journal of Neural Transmission

IS - 12

ER -

CSF inositol does not predict antidepressant response to inositol

Abstract

Keywords

ASJC Scopus subject areas

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