Abstract
CSF inositol was reported to be reduced in depression and inositol has been reported to be effective in treatment of depression. We studied CSF inositol in 18 drug-free depressed patients and 36 normal controls; the depressed patients then participated in an open trial of 18 gm daily inositol treatment for 4 weeks. There was no difference in pre-treatment CSF inositol between depressed patients and controls. CSF inositol levels did not predict response on the Hamilton Depression Scale to 4 weeks of inositol treatment.
| Original language | English |
|---|---|
| Pages (from-to) | 1457-1462 |
| Number of pages | 6 |
| Journal | Journal of Neural Transmission |
| Volume | 103 |
| Issue number | 12 |
| DOIs | |
| State | Published - 1 Dec 1996 |
Keywords
- CSF
- Depression
- Inositol
ASJC Scopus subject areas
- Neurology
- Clinical Neurology
- Psychiatry and Mental health
- Biological Psychiatry
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