Cu(II)/PTABS-Promoted, Chemoselective Amination of HaloPyrimidines

Vikram Phulwale; Harshita Shet; Krishna Chaitanya Gunturu; Smruti Rekha Rout; Rambabu Dandela; Suyog Adhav; Anant R. Kapdi

doi:10.1021/acs.joc.4c00171

Cu(II)/PTABS-Promoted, Chemoselective Amination of HaloPyrimidines

Vikram Phulwale, Harshita Shet, Krishna Chaitanya Gunturu, Smruti Rekha Rout, Rambabu Dandela, Suyog Adhav, Anant R. Kapdi

Research output: Contribution to journal › Article › peer-review

Abstract

Chemoselective amination is a highly desired synthetic methodology, given its importance as a possible strategy to synthesize various drug molecules and agrochemicals. We, herein, disclose a highly chemoselective Cu(II)-PTABS-promoted amination of pyrimidine structural feature containing different halogen atoms.

Original language	English
Pages (from-to)	9243-9254
Number of pages	12
Journal	Journal of Organic Chemistry
Volume	89
Issue number	13
DOIs	https://doi.org/10.1021/acs.joc.4c00171
State	Published - 5 Jul 2024
Externally published	Yes

ASJC Scopus subject areas

Organic Chemistry

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abstract = "Chemoselective amination is a highly desired synthetic methodology, given its importance as a possible strategy to synthesize various drug molecules and agrochemicals. We, herein, disclose a highly chemoselective Cu(II)-PTABS-promoted amination of pyrimidine structural feature containing different halogen atoms.",

author = "Vikram Phulwale and Harshita Shet and Gunturu, {Krishna Chaitanya} and Rout, {Smruti Rekha} and Rambabu Dandela and Suyog Adhav and Kapdi, {Anant R.}",

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T1 - Cu(II)/PTABS-Promoted, Chemoselective Amination of HaloPyrimidines

AU - Phulwale, Vikram

AU - Shet, Harshita

AU - Gunturu, Krishna Chaitanya

AU - Rout, Smruti Rekha

AU - Dandela, Rambabu

AU - Adhav, Suyog

AU - Kapdi, Anant R.

PY - 2024/7/5

Y1 - 2024/7/5

N2 - Chemoselective amination is a highly desired synthetic methodology, given its importance as a possible strategy to synthesize various drug molecules and agrochemicals. We, herein, disclose a highly chemoselective Cu(II)-PTABS-promoted amination of pyrimidine structural feature containing different halogen atoms.

AB - Chemoselective amination is a highly desired synthetic methodology, given its importance as a possible strategy to synthesize various drug molecules and agrochemicals. We, herein, disclose a highly chemoselective Cu(II)-PTABS-promoted amination of pyrimidine structural feature containing different halogen atoms.

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U2 - 10.1021/acs.joc.4c00171

DO - 10.1021/acs.joc.4c00171

M3 - Article

C2 - 38878304

AN - SCOPUS:85196412584

SN - 0022-3263

VL - 89

SP - 9243

EP - 9254

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 13

ER -

Cu(II)/PTABS-Promoted, Chemoselective Amination of HaloPyrimidines

Abstract

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