Cyclic endiamino peptides: A new synthesis of imidazopyrazines

Yael Kogon, Lee Goren, Doron Pappo, Amira Rudi, Yoel Kashman

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


By applying the cyclic endiamino cyclisation methodology to linear tripeptides embodying a β-turn-directing amino acid, the imidazopyrazine ring system was afforded. A mechanism involving the originally desired nine-membered cyclic encliamine is suggested.

Original languageEnglish
Pages (from-to)1852-1854
Number of pages3
JournalEuropean Journal of Organic Chemistry
Issue number12
StatePublished - 1 Apr 2009
Externally publishedYes


  • Cyclization
  • Enols
  • Nitrogen heterocycles
  • Peptides

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry


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