Cyclic endiamino peptides: A new synthesis of imidazopyrazines

Yael Kogon, Lee Goren, Doron Pappo, Amira Rudi, Yoel Kashman

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

By applying the cyclic endiamino cyclisation methodology to linear tripeptides embodying a β-turn-directing amino acid, the imidazopyrazine ring system was afforded. A mechanism involving the originally desired nine-membered cyclic encliamine is suggested.

Original languageEnglish
Pages (from-to)1852-1854
Number of pages3
JournalEuropean Journal of Organic Chemistry
Issue number12
DOIs
StatePublished - 1 Apr 2009
Externally publishedYes

Keywords

  • Cyclization
  • Enols
  • Nitrogen heterocycles
  • Peptides

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