Cyclotron production of 211At/211gPo by 209Bi(α,2n) reaction

S. Morzenti; M. L. Bonardi; F. Groppi; C. Zona; E. Persico; E. Menapace; Z. B. Alfassi

doi:10.1007/s10967-008-0642-6

Cyclotron production of ²¹¹At/^211gPo by ²⁰⁹Bi(α,2n) reaction

S. Morzenti, M. L. Bonardi, F. Groppi, C. Zona, E. Persico, E. Menapace, Z. B. Alfassi

Unit of Nuclear Engineering

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Astatine-211 (T_1/2 = 7.214 h) is an α-emitter at secular equilibrium by EC with its ultra-short-lived α-emitting daughter, polonium-211g (T_1/2 = 0.516 s), with a high Linear Energy Transfer (LET - 130 eV•nm^-1) and a half-life suitable for metabolic radiotherapy; the overall α branching of the ²¹¹At/ ^211gPo system is 100%. The direct production of ²⁰⁹Bi(α,2n)²¹¹At/^211gPo seems the most satisfactory method; Bi targets were irradiated at JRC-Ispra Cyclotron of European Commission, EC, using α-energy higher than 28.61 MeV in order to produce, via ²⁰⁹Bi(α,3n) reaction, small amounts of the γ-emitter ²¹⁰At (used as internal spike).

Original language	English
Pages (from-to)	843-847
Number of pages	5
Journal	Journal of Radioanalytical and Nuclear Chemistry
Volume	276
Issue number	3
DOIs	https://doi.org/10.1007/s10967-008-0642-6
State	Published - 1 Jun 2008

ASJC Scopus subject areas

Analytical Chemistry
Nuclear Energy and Engineering
Radiology Nuclear Medicine and imaging
Pollution
Spectroscopy
Public Health, Environmental and Occupational Health
Health, Toxicology and Mutagenesis

Access to Document

10.1007/s10967-008-0642-6

Cite this

@article{658b161e362b4156a74f0acf4fca5b03,

title = "Cyclotron production of 211At/211gPo by 209Bi(α,2n) reaction",

abstract = "Astatine-211 (T1/2 = 7.214 h) is an α-emitter at secular equilibrium by EC with its ultra-short-lived α-emitting daughter, polonium-211g (T1/2 = 0.516 s), with a high Linear Energy Transfer (LET - 130 eV•nm-1) and a half-life suitable for metabolic radiotherapy; the overall α branching of the 211At/ 211gPo system is 100%. The direct production of 209Bi(α,2n)211At/211gPo seems the most satisfactory method; Bi targets were irradiated at JRC-Ispra Cyclotron of European Commission, EC, using α-energy higher than 28.61 MeV in order to produce, via 209Bi(α,3n) reaction, small amounts of the γ-emitter 210At (used as internal spike).",

author = "S. Morzenti and Bonardi, {M. L.} and F. Groppi and C. Zona and E. Persico and E. Menapace and Alfassi, {Z. B.}",

note = "Funding Information: The present research work was funded in the mainframe of the experiment ASTATO of the Commission V of INFN and the MIUR, Italy. The contributions of JRC-Ispra of European Community and ENEA-Bologna were substantial.",

year = "2008",

month = jun,

day = "1",

doi = "10.1007/s10967-008-0642-6",

language = "English",

volume = "276",

pages = "843--847",

journal = "Journal of Radioanalytical and Nuclear Chemistry",

issn = "0236-5731",

publisher = "Akademiai Kiado ZRt.",

number = "3",

}

TY - JOUR

T1 - Cyclotron production of 211At/211gPo by 209Bi(α,2n) reaction

AU - Morzenti, S.

AU - Bonardi, M. L.

AU - Groppi, F.

AU - Zona, C.

AU - Persico, E.

AU - Menapace, E.

AU - Alfassi, Z. B.

N1 - Funding Information: The present research work was funded in the mainframe of the experiment ASTATO of the Commission V of INFN and the MIUR, Italy. The contributions of JRC-Ispra of European Community and ENEA-Bologna were substantial.

PY - 2008/6/1

Y1 - 2008/6/1

N2 - Astatine-211 (T1/2 = 7.214 h) is an α-emitter at secular equilibrium by EC with its ultra-short-lived α-emitting daughter, polonium-211g (T1/2 = 0.516 s), with a high Linear Energy Transfer (LET - 130 eV•nm-1) and a half-life suitable for metabolic radiotherapy; the overall α branching of the 211At/ 211gPo system is 100%. The direct production of 209Bi(α,2n)211At/211gPo seems the most satisfactory method; Bi targets were irradiated at JRC-Ispra Cyclotron of European Commission, EC, using α-energy higher than 28.61 MeV in order to produce, via 209Bi(α,3n) reaction, small amounts of the γ-emitter 210At (used as internal spike).

AB - Astatine-211 (T1/2 = 7.214 h) is an α-emitter at secular equilibrium by EC with its ultra-short-lived α-emitting daughter, polonium-211g (T1/2 = 0.516 s), with a high Linear Energy Transfer (LET - 130 eV•nm-1) and a half-life suitable for metabolic radiotherapy; the overall α branching of the 211At/ 211gPo system is 100%. The direct production of 209Bi(α,2n)211At/211gPo seems the most satisfactory method; Bi targets were irradiated at JRC-Ispra Cyclotron of European Commission, EC, using α-energy higher than 28.61 MeV in order to produce, via 209Bi(α,3n) reaction, small amounts of the γ-emitter 210At (used as internal spike).

UR - http://www.scopus.com/inward/record.url?scp=45849143642&partnerID=8YFLogxK

U2 - 10.1007/s10967-008-0642-6

DO - 10.1007/s10967-008-0642-6

M3 - Article

AN - SCOPUS:45849143642

SN - 0236-5731

VL - 276

SP - 843

EP - 847

JO - Journal of Radioanalytical and Nuclear Chemistry

JF - Journal of Radioanalytical and Nuclear Chemistry

IS - 3

ER -

Cyclotron production of ²¹¹At/^211gPo by ²⁰⁹Bi(α,2n) reaction

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this