Deciphering the Potential of RNAi Technology as Modulator of Plant Secondary Metabolites with Biomedical Significance

Sicon Mitra, Mimosa Ghorai, Vineet Kumar, Sayanti Mandal, Niraj Kumar Jha, Muddasarul Hoda, Satarupa Dey, Uttpal Anand, Arabinda Ghosh, Potshangbam Nongdam, Mahipal S. Shekhawat, Devendra Kumar Pandey, Mallappa Kumara Swamy, Abhijit Dey

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


RNA interference (RNAi) is a technique of gene silencing mediated by dsRNA. In plants, this dsRNA-induced sequence-specific RNA destruction process is known as posttranscriptional gene silencing (PTGS). RNA interference technique already has a significant influence on the understanding and modification of secondary metabolites in plants. RNAi has mostly been employed to develop therapeutic plants having novel chemical phenotypes, as well as to discover the traits of genes involved in the production of several pharmacologically significant secondary metabolites. In this chapter, the uses of RNAi technology involved in plants like Centella asiatica, Artemisia annua, Panax notoginseng, Rehmannia glutinosa, Isatis indigotica, Brassica napus, Panicum virgatum, Papaver somniferum, Populus sp., Betula platyphylla, and Nicotiana tabacum have been briefly described. In addition, the present status of research and future directions of relevant research are discussed.

Original languageEnglish
Title of host publicationPhytochemical Genomics
Subtitle of host publicationPlant Metabolomics and Medicinal Plant Genomics
PublisherSpringer Nature
Number of pages14
ISBN (Electronic)9789811957796
ISBN (Print)9789811957789
StatePublished - 1 Jan 2023


  • Medicinal plants
  • Posttranscriptional gene silencing
  • RNA interference
  • Secondary metabolites

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (all)
  • Biochemistry, Genetics and Molecular Biology (all)
  • Medicine (all)


Dive into the research topics of 'Deciphering the Potential of RNAi Technology as Modulator of Plant Secondary Metabolites with Biomedical Significance'. Together they form a unique fingerprint.

Cite this