Decline in the prevalence of antibodies to herpes simplex virus types 1 and 2 among Israeli young adults between 1984 and 2002

Batya B. Davidovici, Itamar Grotto, Ran D. Balicer, Noah J. Robinson, Dani Cohen

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

OBJECTIVE: The objective of this study was to estimate the seroprevalence of herpes simplex virus (HSV) types 1 and 2 in male and female soldiers discharged from the Israel Defense Force (IDF) over a period of 18 years. GOAL: The goal of this study was to study the secular trends of HSV-1 and HSV-2 infection rates in Israeli young adults. STUDY DESIGN: Three consecutive cross-sectional studies were carried out on stored sera of systematic random samples of soldiers (median age = 20.8) discharged from the IDF in 1984-1985, 1992-1993, and 2001-2002. HSV-1 and -2 seroprevalence was analyzed using indirect IgG enzyme-linked immunosorbent assay for type-specific antibodies. RESULTS: There was a significant decrease in HSV-1 and HSV-2 seropositivity rates at discharge from the army and an estimated 10-fold decline in the incidence rates of HSV-2 infection during the military service over the last 2 decades. CONCLUSIONS: The decline in HSV-1 seroprevalence rate is similar to that reported from other industrialized countries. The decrease in HSV-2 seroprevalence and transmission rates among Israeli young adults is steeper than that reported from Western countries.

Original languageEnglish
Pages (from-to)641-645
Number of pages5
JournalSexually Transmitted Diseases
Volume33
Issue number11
DOIs
StatePublished - 1 Nov 2006

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Infectious Diseases

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