Deep transcranial magnetic stimulation for obsessive-compulsive disorder is efficacious even in patients who failed multiple medications and CBT

Yiftach Roth; Noam Barnea-Ygael; Lior Carmi; Eric A. Storch; Aron Tendler; Abraham Zangen

doi:10.1016/j.psychres.2020.113179

Deep transcranial magnetic stimulation for obsessive-compulsive disorder is efficacious even in patients who failed multiple medications and CBT

Yiftach Roth, Noam Barnea-Ygael, Lior Carmi, Eric A. Storch, Aron Tendler, Abraham Zangen

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

OCD is a chronic and disabling disease with a lifetime prevalence of 2%-3%. About 40–60% of these patients do not adequately respond to pharmacotherapy and CBT. Deep transcranial magnetic stimulation (dTMS) was shown to be safe and effective as a treatment alternative for OCD and recently received regulatory approvals. Yet it is unclear whether patients who failed numerous medications and/or CBT can still benefit from dTMS. Here, we analyzed recent data from a double-blind multicenter dTMS study and found efficacy of this novel treatment even in OCD patient cohorts who previously failed to respond to multiple medications and CBT.

Original language	English
Article number	113179
Journal	Psychiatry Research
Volume	290
DOIs	https://doi.org/10.1016/j.psychres.2020.113179
State	Published - 1 Aug 2020

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry

Access to Document

10.1016/j.psychres.2020.113179

Cite this

@article{0030b2ec0eb84ae587612a9c6703be4f,

title = "Deep transcranial magnetic stimulation for obsessive-compulsive disorder is efficacious even in patients who failed multiple medications and CBT",

abstract = "OCD is a chronic and disabling disease with a lifetime prevalence of 2%-3%. About 40–60% of these patients do not adequately respond to pharmacotherapy and CBT. Deep transcranial magnetic stimulation (dTMS) was shown to be safe and effective as a treatment alternative for OCD and recently received regulatory approvals. Yet it is unclear whether patients who failed numerous medications and/or CBT can still benefit from dTMS. Here, we analyzed recent data from a double-blind multicenter dTMS study and found efficacy of this novel treatment even in OCD patient cohorts who previously failed to respond to multiple medications and CBT.",

author = "Yiftach Roth and Noam Barnea-Ygael and Lior Carmi and Storch, {Eric A.} and Aron Tendler and Abraham Zangen",

note = "Publisher Copyright: {\textcopyright} 2020 The Authors",

year = "2020",

month = aug,

day = "1",

doi = "10.1016/j.psychres.2020.113179",

language = "English",

volume = "290",

journal = "Psychiatry Research",

issn = "0165-1781",

publisher = "Elsevier Ireland Ltd",

}

TY - JOUR

T1 - Deep transcranial magnetic stimulation for obsessive-compulsive disorder is efficacious even in patients who failed multiple medications and CBT

AU - Roth, Yiftach

AU - Barnea-Ygael, Noam

AU - Carmi, Lior

AU - Storch, Eric A.

AU - Tendler, Aron

AU - Zangen, Abraham

PY - 2020/8/1

Y1 - 2020/8/1

N2 - OCD is a chronic and disabling disease with a lifetime prevalence of 2%-3%. About 40–60% of these patients do not adequately respond to pharmacotherapy and CBT. Deep transcranial magnetic stimulation (dTMS) was shown to be safe and effective as a treatment alternative for OCD and recently received regulatory approvals. Yet it is unclear whether patients who failed numerous medications and/or CBT can still benefit from dTMS. Here, we analyzed recent data from a double-blind multicenter dTMS study and found efficacy of this novel treatment even in OCD patient cohorts who previously failed to respond to multiple medications and CBT.

AB - OCD is a chronic and disabling disease with a lifetime prevalence of 2%-3%. About 40–60% of these patients do not adequately respond to pharmacotherapy and CBT. Deep transcranial magnetic stimulation (dTMS) was shown to be safe and effective as a treatment alternative for OCD and recently received regulatory approvals. Yet it is unclear whether patients who failed numerous medications and/or CBT can still benefit from dTMS. Here, we analyzed recent data from a double-blind multicenter dTMS study and found efficacy of this novel treatment even in OCD patient cohorts who previously failed to respond to multiple medications and CBT.

UR - http://www.scopus.com/inward/record.url?scp=85086433079&partnerID=8YFLogxK

U2 - 10.1016/j.psychres.2020.113179

DO - 10.1016/j.psychres.2020.113179

M3 - Article

C2 - 32540588

AN - SCOPUS:85086433079

SN - 0165-1781

VL - 290

JO - Psychiatry Research

JF - Psychiatry Research

M1 - 113179

ER -

Deep transcranial magnetic stimulation for obsessive-compulsive disorder is efficacious even in patients who failed multiple medications and CBT

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this