Delirium during heroin withdrawal with doxepin: A short report

Yoram Barak; Joseph Levine; Yair Lampl; Avner Elizur

doi:10.1002/hup.470100211

Delirium during heroin withdrawal with doxepin: A short report

Yoram Barak, Joseph Levine, Yair Lampl, Avner Elizur

Research output: Contribution to journal › Article › peer-review

Abstract

Doxepin was evaluated in a group of 10 patients for its efficacy in decreasing withdrawal symptoms during ambulatory heroin withdrawal. Although no subjective relief was reported by the subjects, during the 10 days trial, four of the patients developed full blown delirium during the trial's first three days. Since delirium is rarely one of the complications of heroin withdrawal the question whether doxepin enhanced or induced its appearance in these patients, remains unanswered. Until this issue is resolved we suggest cessation of doxepin usage in the initial withdrawal phase from heroin.

Original language	English
Pages (from-to)	149-151
Number of pages	3
Journal	Human Psychopharmacology
Volume	10
Issue number	2
DOIs	https://doi.org/10.1002/hup.470100211
State	Published - 1 Jan 1995
Externally published	Yes

Keywords

delirium
doxepin
heroin withdrawal

ASJC Scopus subject areas

Neurology
Clinical Neurology
Psychiatry and Mental health
Pharmacology (medical)

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10.1002/hup.470100211

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abstract = "Doxepin was evaluated in a group of 10 patients for its efficacy in decreasing withdrawal symptoms during ambulatory heroin withdrawal. Although no subjective relief was reported by the subjects, during the 10 days trial, four of the patients developed full blown delirium during the trial's first three days. Since delirium is rarely one of the complications of heroin withdrawal the question whether doxepin enhanced or induced its appearance in these patients, remains unanswered. Until this issue is resolved we suggest cessation of doxepin usage in the initial withdrawal phase from heroin.",

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AU - Lampl, Yair

AU - Elizur, Avner

PY - 1995/1/1

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AB - Doxepin was evaluated in a group of 10 patients for its efficacy in decreasing withdrawal symptoms during ambulatory heroin withdrawal. Although no subjective relief was reported by the subjects, during the 10 days trial, four of the patients developed full blown delirium during the trial's first three days. Since delirium is rarely one of the complications of heroin withdrawal the question whether doxepin enhanced or induced its appearance in these patients, remains unanswered. Until this issue is resolved we suggest cessation of doxepin usage in the initial withdrawal phase from heroin.

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Delirium during heroin withdrawal with doxepin: A short report

Abstract

Keywords

ASJC Scopus subject areas

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